{"id":"W2339806509","doi":"10.1021/acs.est.6b00490","title":"High Conservation in Transcriptomic and Proteomic Response of White Sturgeon to Equipotent Concentrations of 2,3,7,8-TCDD, PCB 77, and Benzo[a]pyrene","year":2016,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"Aryl hydrocarbon receptor; Transcriptome; Sturgeon; Proteome; Pyrene; Benzo(a)pyrene; Chemistry; Biology; Fish <Actinopterygii>; Biochemistry; Gene expression; Gene; Fishery; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008743527,0.0002374559,0.0002383155,0.0003206044,0.0001616107,0.0002155337,0.00008957217,0.0002817774,0.0006937105],"category_scores_gemma":[0.0001174863,0.0001546103,0.0003469221,0.0002093223,0.0001990349,0.0001897283,0.000285932,0.0002677257,0.0001826449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001478352,"about_ca_system_score_gemma":0.0001644515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007489488,"about_ca_topic_score_gemma":0.001370542,"domain_scores_codex":[0.9998996,0.000006985601,0.000006413772,0.00004513481,0.00002640671,0.00001535526],"domain_scores_gemma":[0.9999237,0.00001099937,0.00002282873,0.000006897261,0.00001679607,0.00001868441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007427222,0.000005283504,0.001861638,0.00001987994,0.000008241151,0.00004183023,0.0000246391,0.00002746694,0.9974016,0.00001589698,0.00001859588,0.0005006862],"study_design_scores_gemma":[0.00001677112,0.0006082279,0.8353179,0.0000110294,0.0000842908,0.000683639,0.0003177643,0.001031151,0.1595736,0.0001458431,0.002187631,0.00002221666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970836,0.0004286638,0.0008133221,0.00005054544,0.00001138023,0.000009852739,0.0009433595,0.00002891637,0.000630311],"genre_scores_gemma":[0.992175,0.0004035834,0.001403794,0.000175922,0.000009212597,0.00005113283,0.002833793,0.00001756876,0.002929959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007489488,"threshold_uncertainty_score":0.002320707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005359904534862015,"score_gpt":0.2065709711509109,"score_spread":0.2012110666160489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}