{"id":"W2340323570","doi":"10.2174/1570162x14999160224100541","title":"Apobec3G-Based Strategies to Defeat HIV Infection","year":2016,"lang":"en","type":"review","venue":"Current HIV Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"APOBEC3G; Cytidine deaminase; Innate immune system; Biology; SAMHD1; Immunity; Virology; Immunology; Evasion (ethics); Acquired immune system; Immune system; Human immunodeficiency virus (HIV); Reverse transcriptase; Antibody; Genetics; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001841992,0.0006171169,0.001343413,0.001614866,0.0006097545,0.0001847177,0.0007899912,0.0005954187,0.003346559],"category_scores_gemma":[0.0006478504,0.0003968981,0.0006019573,0.0009789519,0.0005133891,0.0001385282,0.0004684383,0.001982705,0.1763843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007802168,"about_ca_system_score_gemma":0.002511924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000525637,"about_ca_topic_score_gemma":0.00004161921,"domain_scores_codex":[0.9930665,0.003098537,0.0006173046,0.0010728,0.0003609605,0.001783931],"domain_scores_gemma":[0.9962351,0.001896159,0.0001201157,0.001054934,0.0004413563,0.0002523809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005301749,0.0003403662,0.00005633226,0.004475786,0.0002610342,0.00001858897,0.00003132997,4.26585e-7,0.00001597105,0.0003716408,0.1146828,0.8796927],"study_design_scores_gemma":[0.0007862974,0.000305457,0.00002215535,0.009598513,0.00009686225,0.00002002648,0.00001421956,2.19533e-7,0.00005018963,0.00004288758,0.9886875,0.0003757369],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002021725,0.9913669,0.0006235591,0.0001800413,0.001020728,0.002297539,0.001264332,0.0001431846,0.003083555],"genre_scores_gemma":[0.0001534459,0.9880703,0.00001516921,0.000003503865,0.0002414403,0.001749625,0.003076936,0.00008170194,0.006607883],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.879317,"threshold_uncertainty_score":0.9998483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2019572904176248,"score_gpt":0.4816731365333349,"score_spread":0.2797158461157101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}