{"id":"W2340438092","doi":"10.1002/pro.2936","title":"Conformational characterization of the intrinsically disordered protein Chibby: Interplay between structural elements in target recognition","year":2016,"lang":"en","type":"article","venue":"Protein Science","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Coiled coil; Biology; Biophysics; Terminal (telecommunication); LIM domain; Plasma protein binding; Intrinsically disordered proteins; Cell biology; Transcription factor; Biochemistry; Crystallography; Chemistry; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001154132,0.0001681117,0.0001196569,0.0001190288,0.0001786627,0.0001374674,0.0001716152,0.0001565487,0.0004973891],"category_scores_gemma":[0.0001739602,0.00006456413,0.0001011998,0.0001474747,0.0002358779,0.0001280742,0.0001373719,0.0003657441,0.000138202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002116661,"about_ca_system_score_gemma":0.0001382213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001212111,"about_ca_topic_score_gemma":0.001080149,"domain_scores_codex":[0.9999479,0.000006285009,0.000003257878,0.00001392939,0.00001597381,0.00001266175],"domain_scores_gemma":[0.9998858,0.0000238347,0.00002675852,0.000009599582,0.00001904225,0.00003499333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007773111,0.00001803254,0.0007923811,0.00001856665,0.000003873412,0.00005339289,0.00003021207,0.0001946272,0.9981626,0.00006325018,0.00003061313,0.0005548222],"study_design_scores_gemma":[0.00002335311,0.0002281985,0.02646802,0.000007755918,0.00002488649,0.0007090688,0.0001638963,0.00727468,0.962973,0.0001463232,0.001963102,0.00001772732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983922,0.0002255643,0.0009281724,0.00002956269,0.000002353685,0.000004757291,0.0001818728,0.000007083613,0.0002284381],"genre_scores_gemma":[0.9971868,0.0002434273,0.001349776,0.00004022372,0.000003691655,0.000007773881,0.0006856411,0.00001161897,0.0004711266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001212111,"threshold_uncertainty_score":0.002410114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008952602768412088,"score_gpt":0.2528608570544595,"score_spread":0.2439082542860474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}