{"id":"W2340692535","doi":"10.1021/acsbiomaterials.6b00085","title":"Cationic Galactose-Conjugated Copolymers for Epidermal Growth Factor (EGFR) Knockdown in Cervical Adenocarcinoma","year":2016,"lang":"en","type":"article","venue":"ACS Biomaterials Science & Engineering","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates - Health Solutions","keywords":"Methacrylamide; Raft; Glycopolymer; Copolymer; Chain transfer; HeLa; Agarose gel electrophoresis; Cationic polymerization; Chemistry; Biophysics; Materials science; Polymer chemistry; Biochemistry; Polymer; Biology; Acrylamide; Cell; Organic chemistry; Radical polymerization; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001344913,0.0002148429,0.0001447289,0.0001452896,0.00008897361,0.0001500646,0.0001168972,0.0001558936,0.0006399414],"category_scores_gemma":[0.000122273,0.0001071317,0.0001084999,0.0001084811,0.00009828911,0.0001499194,0.0001409763,0.0002363973,0.0002055083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002325934,"about_ca_system_score_gemma":0.0002134558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005343892,"about_ca_topic_score_gemma":0.0009869232,"domain_scores_codex":[0.9999447,0.00001062824,0.000004797266,0.000009563706,0.00001760999,0.0000127359],"domain_scores_gemma":[0.9999565,0.000007728017,0.00001287323,0.000004136683,0.000007472207,0.00001130216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002694262,0.000008454313,0.00004353225,0.00001274355,0.00000122485,0.00001317572,0.000003767569,0.00007927242,0.9985096,0.00004076934,0.00001214664,0.001248499],"study_design_scores_gemma":[0.00001364776,0.0002823887,0.001136813,0.000002879759,0.00001106267,0.0001110971,0.000004691097,0.0009573657,0.9960482,0.00001913862,0.001410399,0.00000236936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925082,0.001704246,0.004082958,0.00005909672,0.00001521761,0.00005312148,0.000099137,0.00006423226,0.00141359],"genre_scores_gemma":[0.9941209,0.0008381017,0.003400591,0.00002441156,0.000005219296,0.00003543153,0.0001107806,0.00001545011,0.001449115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006399414,"threshold_uncertainty_score":0.00214082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198125137839081,"score_gpt":0.2413436172023435,"score_spread":0.2293623658239526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}