{"id":"W2340692535","doi":"10.1021/acsbiomaterials.6b00085","title":"Cationic Galactose-Conjugated Copolymers for Epidermal Growth Factor (EGFR) Knockdown in Cervical Adenocarcinoma","year":2016,"lang":"en","type":"article","venue":"ACS Biomaterials Science & Engineering","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates - Health Solutions","keywords":"Methacrylamide; Raft; Glycopolymer; Copolymer; Chain transfer; HeLa; Agarose gel electrophoresis; Cationic polymerization; Chemistry; Biophysics; Materials science; Polymer chemistry; Biochemistry; Polymer; Biology; Acrylamide; Cell; Organic chemistry; Radical polymerization; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002691331,0.0001885064,0.0001816533,0.0001636207,0.00007423647,0.0000732151,0.000433366,0.00011982,0.00003840584],"category_scores_gemma":[0.00025473,0.0001462512,0.0000532025,0.0002078875,0.0001490599,0.00004193243,0.0001191618,0.00001837448,0.00002235673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006503847,"about_ca_system_score_gemma":0.000143953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005084109,"about_ca_topic_score_gemma":0.00001134249,"domain_scores_codex":[0.9985299,0.00001813874,0.0003128649,0.0004733343,0.0001443201,0.0005214279],"domain_scores_gemma":[0.9994017,0.00002768366,0.0000661726,0.0002706186,0.0001156083,0.000118257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003683041,0.00001415648,0.004762582,0.00001222533,0.000008016313,0.000001562302,0.00003887128,0.00001466476,0.9946926,0.0001616451,0.00005157763,0.0002052996],"study_design_scores_gemma":[0.0004446892,0.0001485962,0.04773826,0.00003216306,0.000004556213,0.00001152315,0.00001284338,0.0000631607,0.9510968,0.00001949493,0.0002047194,0.0002231397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996581,0.0001675852,0.002173381,0.0002049793,0.0005411694,0.0002235738,0.0000560847,0.00003163282,0.00002063782],"genre_scores_gemma":[0.9992832,0.00005535021,0.0002771807,0.00007380576,0.0001636072,0.000059548,0.00002391264,0.00002072183,0.00004267183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04359572,"threshold_uncertainty_score":0.5963951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198125137839081,"score_gpt":0.2413436172023435,"score_spread":0.2293623658239526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}