{"id":"W2340787285","doi":"10.18632/oncotarget.8612","title":"Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress","year":2016,"lang":"en","type":"article","venue":"Oncotarget","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Canada's Michael Smith Genome Sciences Centre; Hospital for Sick Children; BC Cancer Agency; University of Toronto","funders":"National Cancer Institute; Hospital for Sick Children; Garron Family Cancer Centre; Brain Tumour Research; National Institute of General Medical Sciences; Bundesministerium für Bildung und Forschung; Genome British Columbia; Harvard University; Genome Canada; National Institutes of Health; Children's Hospital Foundation; Deutsche Krebshilfe; Johns Hopkins University","keywords":"Medulloblastoma; Medicine; Sick child; Gerontology; Pediatrics; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001277828,0.0003606822,0.0003257025,0.0002499112,0.0003182604,0.0003529973,0.0002163994,0.0003649378,0.002605743],"category_scores_gemma":[0.0002536935,0.0001178079,0.0004277185,0.0002499045,0.0003882365,0.0001437064,0.0003168354,0.0007392097,0.0005336954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004285039,"about_ca_system_score_gemma":0.0003287525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002433989,"about_ca_topic_score_gemma":0.004507317,"domain_scores_codex":[0.999862,0.00001650056,0.00001671667,0.00003980689,0.00003150859,0.00003355569],"domain_scores_gemma":[0.9998891,0.00001352676,0.0000441023,0.000009182259,0.000007635196,0.00003646793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009127494,0.00009118498,0.009908997,0.00007909748,0.00007711128,0.002808734,0.00008674004,0.0003461386,0.977748,0.0006861471,0.001383369,0.005871603],"study_design_scores_gemma":[0.0003477671,0.001209895,0.3133479,0.0001174927,0.0003853067,0.01812754,0.000780174,0.006008809,0.6334692,0.001982446,0.02409905,0.0001244747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954888,0.0008449823,0.000987181,0.0002866076,0.0001264438,0.00001813511,0.0008556833,0.00007663696,0.001315579],"genre_scores_gemma":[0.9975213,0.0003250887,0.0003621608,0.0001437506,0.00001586596,0.00001464512,0.0005002826,0.00004937207,0.001067479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002605743,"threshold_uncertainty_score":0.00871706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00483319641360028,"score_gpt":0.2208219647564295,"score_spread":0.2159887683428292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}