{"id":"W2340791212","doi":"10.1093/humrep/dew030","title":"HT-COMET: a novel automated approach for high throughput assessment of human sperm chromatin quality","year":2016,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Centre in Green Chemistry and Catalysis; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University","keywords":"Comet assay; Comet; Sperm; DNA damage; Biology; Andrology; Medicine; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003641598,0.001045412,0.001281483,0.003228221,0.0004418134,0.001698203,0.001483311,0.001156488,0.0035407],"category_scores_gemma":[0.003681215,0.0007028299,0.0007821434,0.001522634,0.0006573065,0.00123073,0.0008668078,0.0009586092,0.00188485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005980437,"about_ca_system_score_gemma":0.0006225466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006128387,"about_ca_topic_score_gemma":0.001378366,"domain_scores_codex":[0.9964871,0.001031494,0.0002057125,0.0006052977,0.001544101,0.0001261857],"domain_scores_gemma":[0.9965366,0.0009788899,0.0007905797,0.0004920008,0.001014005,0.0001878336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001247778,0.0004905572,0.0263753,0.001747167,0.000648489,0.0003670111,0.000311854,0.002695436,0.6671791,0.001560089,0.009572934,0.2878042],"study_design_scores_gemma":[0.0003998047,0.004943429,0.1165826,0.0001675771,0.0006591801,0.004548284,0.0002428965,0.06384379,0.7675813,0.002724061,0.03790053,0.0004065921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1635069,0.01149683,0.7967836,0.002160093,0.0006742669,0.002837989,0.006796451,0.01041724,0.005326657],"genre_scores_gemma":[0.290606,0.005309596,0.6858115,0.001026501,0.0007486035,0.002858012,0.007218004,0.0004508319,0.005970958],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003641598,"threshold_uncertainty_score":0.01925886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08640255881572778,"score_gpt":0.3850751661965844,"score_spread":0.2986726073808567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}