{"id":"W2340925103","doi":"10.1158/1557-3265.ovcasymp14-poster-ther-1415","title":"Abstract POSTER-THER-1415: Translational study of DPX-survivac peptide vaccine and metronomic cyclophosphamide using a novel HLA-A2/ survivin expressing ovarian tumor model to mimic phase I clinical data","year":2015,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; Dalhousie University; Immunovaccine (Canada)","funders":"","keywords":"Survivin; Ovarian cancer; Cancer research; Peptide vaccine; ELISPOT; Immune system; Immunology; Cytotoxic T cell; In vivo; Medicine; Cancer; Biology; T cell; Antigen; Internal medicine; In vitro; Epitope","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002645045,0.0004278932,0.0004886499,0.000203095,0.0001763026,0.0003051324,0.0002598636,0.0004270285,0.002749454],"category_scores_gemma":[0.00009411986,0.0001155072,0.0003874637,0.0001343079,0.0002393229,0.0002924365,0.0001498998,0.001069991,0.0004858148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003100463,"about_ca_system_score_gemma":0.0005022996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005142843,"about_ca_topic_score_gemma":0.0004428084,"domain_scores_codex":[0.9998642,0.00002217161,0.000008956225,0.00003159574,0.0000241521,0.00004888559],"domain_scores_gemma":[0.9999119,0.000008051372,0.00001339999,0.000009480105,0.000009720499,0.00004747911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01181713,0.009566875,0.0005630446,0.00023644,0.00005880626,0.0001585226,0.00006659162,0.0008679956,0.9567565,0.0004125714,0.001053505,0.018442],"study_design_scores_gemma":[0.00407661,0.1806045,0.005987721,0.00002861733,0.0001781758,0.0005151839,0.00008170656,0.003251523,0.7947584,0.0001912353,0.01030756,0.00001870562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943662,0.0007644465,0.001449397,0.000172396,0.0001745451,0.0004642868,0.0005823969,0.00006488197,0.001961643],"genre_scores_gemma":[0.9912075,0.0006151451,0.001752627,0.000150501,0.00006121941,0.0005272847,0.001168289,0.00002431524,0.004493113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002749454,"threshold_uncertainty_score":0.009197831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4938239212117624,"score_gpt":0.54292182611424,"score_spread":0.04909790490247762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}