{"id":"W2341040321","doi":"10.1186/s40478-016-0311-x","title":"Rewiring neuronal microcircuits of the brain via spine head protrusions-a role for synaptopodin and intracellular calcium stores","year":2016,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Université de Lausanne; Deutsche Forschungsgemeinschaft; Deutscher Akademischer Austauschdienst; McGill University; Massachusetts General Hospital","keywords":"Neuroscience; Neurology; Intracellular; Calcium in biology; Synaptopodin; Calcium; Head (geology); Neuronal firing; Medicine; Biology; Cell biology; Electrophysiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005209077,0.0002000833,0.0002337751,0.0001204186,0.00102924,0.00003829172,0.002349077,0.00007542654,0.00001601687],"category_scores_gemma":[0.003758883,0.0001193397,0.0001057135,0.0004559213,0.001877821,0.0002163553,0.001784047,0.0004120587,0.000005803174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000200024,"about_ca_system_score_gemma":0.00007334576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002925068,"about_ca_topic_score_gemma":0.000003400852,"domain_scores_codex":[0.9969442,0.001344461,0.0003870805,0.000609658,0.0002600145,0.0004546131],"domain_scores_gemma":[0.995672,0.002327945,0.0002341441,0.001557142,0.00009313082,0.0001156757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002817854,0.0001741953,0.001335675,0.00001249274,0.000001374054,0.000007202164,0.00007475314,8.901044e-7,0.9931238,0.001205271,0.0001252353,0.003910874],"study_design_scores_gemma":[0.0005392488,0.0003571355,0.02409821,0.00003172436,0.00001573312,0.0001888217,0.000009374638,0.0004008414,0.9635476,0.0006166166,0.0100404,0.0001542721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.963685,0.0001132505,0.0003238953,0.0341844,0.0001475499,0.001248508,0.00006230857,0.00007511055,0.0001599234],"genre_scores_gemma":[0.996391,0.0004420393,0.0001556898,0.00234432,0.00002666126,0.0002399036,5.859927e-7,0.00002825767,0.0003715224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03270597,"threshold_uncertainty_score":0.7916188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1029505145213505,"score_gpt":0.358839925322233,"score_spread":0.2558894108008826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}