{"id":"W2341175725","doi":"10.1002/stem.2373","title":"Paracrine Engineering of Human Explant-Derived Cardiac Stem Cells to Over-Express Stromal-Cell Derived Factor 1α Enhances Myocardial Repair","year":2016,"lang":"en","type":"article","venue":"Stem Cells","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Paracrine signalling; Stromal cell; Stem cell; Biology; Cell biology; Stem cell factor; Angiogenesis; Mesenchymal stem cell; Autocrine signalling; Cancer research; Induced stem cells; Endothelial stem cell; Progenitor cell; Adult stem cell; Immunology; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002376926,0.0003950152,0.000301923,0.0002718419,0.00008777269,0.0003868083,0.0001787936,0.000208612,0.00212249],"category_scores_gemma":[0.0001079051,0.0001698842,0.0003372724,0.0001501777,0.0002694144,0.0001832947,0.0001904749,0.0007524223,0.000831846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000190724,"about_ca_system_score_gemma":0.000288343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002536333,"about_ca_topic_score_gemma":0.0005004503,"domain_scores_codex":[0.9998266,0.0000219252,0.00001381049,0.00003620461,0.00007309824,0.00002836329],"domain_scores_gemma":[0.9998689,0.00002528503,0.00003215856,0.00002341754,0.0000209085,0.00002934916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004765928,0.00003156678,0.0001041432,0.00003028108,0.000003773309,0.00003854376,0.00001881255,0.00006063132,0.9975103,0.00009572234,0.00005003546,0.002008442],"study_design_scores_gemma":[0.00002440321,0.0002875005,0.001470961,0.000007100271,0.00001929787,0.0002088991,0.00001964917,0.0007369875,0.9925205,0.00005487954,0.004646808,0.000003213141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9698009,0.00363233,0.01927799,0.0002115223,0.0001980141,0.0001579378,0.0007129691,0.00043412,0.005574161],"genre_scores_gemma":[0.9851605,0.001507113,0.007061947,0.00007926077,0.00003390541,0.00006535625,0.0006985909,0.00006285639,0.005330431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00212249,"threshold_uncertainty_score":0.007100463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0155117113387434,"score_gpt":0.2396890356831597,"score_spread":0.2241773243444163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}