{"id":"W2341201740","doi":"10.1371/journal.pone.0153615","title":"Differences in Whole Blood Gene Expression Associated with Infection Time-Course and Extent of Fetal Mortality in a Reproductive Model of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Alberta","funders":"Genome Alberta; Genome Prairie; McGill University; Alberta Innovates; University of Alberta; Genome Canada; Alberta Livestock and Meat Agency","keywords":"Biology; Porcine reproductive and respiratory syndrome virus; Innate immune system; Immunology; Chemokine; Arterivirus; Immune system; Interferon; Andrology; Immunity; Fetus; Gene expression; Gene; Virology; Virus; Pregnancy; Internal medicine; Medicine; Genetics; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004114614,0.0001283064,0.0003533121,0.00004781675,0.00006672492,0.000005537314,0.00003211859,0.00007948397,0.00001139333],"category_scores_gemma":[0.0004124359,0.00005241554,0.00001929184,0.0003720059,0.0002106753,0.0002081919,0.00007786094,0.00009315457,8.064272e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003670774,"about_ca_system_score_gemma":0.0000111791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00110427,"about_ca_topic_score_gemma":0.001944606,"domain_scores_codex":[0.9988202,0.0001349717,0.0002723853,0.0004470063,0.000191861,0.0001335356],"domain_scores_gemma":[0.9993747,0.00008154795,0.0002374618,0.00008892256,0.0001884585,0.0000289402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007663631,0.0009046025,0.4888185,0.000008796116,0.00005864327,9.212477e-7,0.00007671403,0.000003920532,0.5098994,0.000002390635,7.534206e-7,0.0001487383],"study_design_scores_gemma":[0.0002978251,0.001202676,0.8273305,0.0002858017,0.00007826737,0.000001946765,0.00002290402,0.00005613827,0.1704465,0.0001815781,1.692608e-7,0.00009566364],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992845,0.0002154882,0.000002230877,0.00006642889,0.00001051933,0.0003247801,0.00003795437,0.0000245973,0.00003347857],"genre_scores_gemma":[0.9996358,0.0001974991,0.00004293733,0.000003879635,0.00002565529,0.00002937111,0.000003648147,0.00000173931,0.00005943754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3394529,"threshold_uncertainty_score":0.2137444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06536997334280607,"score_gpt":0.2360689502657951,"score_spread":0.170698976922989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}