{"id":"W2341302423","doi":"10.1038/cddis.2015.229","title":"CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"China Scholarship Council; Canadian Institutes of Health Research; Ovarian Cancer Canada","keywords":"Necroptosis; Programmed cell death; Cancer research; CD40; Biology; Apoptosis; Serous fluid; Cell biology; Chemistry; Cytotoxic T cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002211908,0.0004117783,0.0003090849,0.0001160068,0.0001374447,0.0001201573,0.0002296076,0.0002354758,0.00001503607],"category_scores_gemma":[0.00003323028,0.0003825699,0.0001168197,0.0001246819,0.00005276944,0.00002204027,0.0001919401,0.0001767381,0.00002451564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003557474,"about_ca_system_score_gemma":0.0003354906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002992816,"about_ca_topic_score_gemma":0.00006367477,"domain_scores_codex":[0.9978843,0.00009153601,0.0003885682,0.0007947302,0.0002873655,0.0005535003],"domain_scores_gemma":[0.9981334,0.00001424371,0.0001510747,0.0005097037,0.0001027157,0.001088862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009171739,0.0009575266,0.00733462,0.0002710178,0.00002720324,0.0003248988,0.0001552125,0.0009725176,0.9876319,0.00009990079,0.0006368757,0.0006711225],"study_design_scores_gemma":[0.006211174,0.0005435469,0.01304937,0.00006621462,0.0001820685,0.0000272474,0.0003119236,0.001999245,0.97013,0.000804787,0.005642401,0.001032039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944106,0.002943995,0.0005815962,0.00009549977,0.0003653619,0.0004848216,0.0001330324,0.00003483959,0.0009501996],"genre_scores_gemma":[0.9939268,0.0005975104,0.0005902154,0.0007560484,0.000264844,0.00003995279,0.0004126242,0.00005955035,0.003352449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01750194,"threshold_uncertainty_score":0.9998626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01339596502421113,"score_gpt":0.2297231381197361,"score_spread":0.2163271730955249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}