{"id":"W2341457709","doi":"10.1371/journal.pone.0140805","title":"Red Blood Cells Preconditioned with Hemin Are Less Permissive to Plasmodium Invasion In Vivo and In Vitro","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université du Québec à Montréal","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies; Université du Québec à Montréal","keywords":"Hemin; Parasitemia; Plasmodium falciparum; Red blood cell; Biology; In vivo; In vitro; Microbiology; Plasmodium chabaudi; Hemoglobin; Heme; Immunology; Molecular biology; Malaria; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007970088,0.0001090565,0.000326858,0.0001643311,0.00001751179,0.000005809089,0.00003218255,0.00009252875,0.00006715536],"category_scores_gemma":[0.00008457564,0.00009338598,0.00001167041,0.0001727621,0.00003131567,0.00005353809,0.00002746187,0.000161594,0.00002026733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004973639,"about_ca_system_score_gemma":0.0000679465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003275528,"about_ca_topic_score_gemma":0.0001706872,"domain_scores_codex":[0.9992257,0.00004285831,0.0001579668,0.0002587953,0.0001541976,0.0001604717],"domain_scores_gemma":[0.9994755,0.00004594261,0.00005417618,0.0001517884,0.0000801081,0.0001924295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003054307,0.001233111,0.008661854,0.0001320571,0.00003313119,0.0001227945,0.0008392907,0.00001814498,0.9852608,0.000001234975,0.0006055983,0.00003767058],"study_design_scores_gemma":[0.005401927,0.0008269627,0.01141288,0.00058527,0.00007022689,0.00002627595,0.0009771331,0.0001241941,0.9803454,0.00003101518,0.00006643154,0.0001323378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975042,0.00004220121,0.000004179925,0.001065969,0.00002946454,0.000444588,0.0000191439,0.00002488306,0.0008654151],"genre_scores_gemma":[0.9964883,0.00002560722,0.001445104,0.0007613769,0.00006640807,0.00006275633,0.00003178296,0.00001561469,0.001103031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004915459,"threshold_uncertainty_score":0.380817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05697603319697032,"score_gpt":0.2313929621801095,"score_spread":0.1744169289831392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}