{"id":"W2341534776","doi":"10.1111/his.12988","title":"Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small‐cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics","year":2016,"lang":"en","type":"article","venue":"Histopathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia; BC Cancer Agency; McGill University Health Centre; University Health Network; University of Toronto; Toronto General Hospital; Jewish General Hospital; McGill University","funders":"National Institute for Health and Care Research","keywords":"SMARCA4; Biology; Immunohistochemistry; Pathology; Staining; Small-cell carcinoma; Ovary; Carcinoma; Gene expression; Medicine; Genetics; Chromatin remodeling; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004633286,0.0002082777,0.0002269966,0.001538788,0.0002314687,0.0003711708,0.0002998409,0.0003745861,0.0009788488],"category_scores_gemma":[0.001100072,0.0002655453,0.0001981629,0.0005943964,0.0005733581,0.0002172385,0.0002871518,0.0001494375,0.0002742266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003140386,"about_ca_system_score_gemma":0.0001880797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009211189,"about_ca_topic_score_gemma":0.001468068,"domain_scores_codex":[0.9997024,0.0000398995,0.00005444168,0.00004841709,0.00008658246,0.00006810294],"domain_scores_gemma":[0.9995161,0.0001257089,0.0001676592,0.00006045904,0.00006731597,0.00006277555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006672554,0.00003533486,0.8000117,0.000147901,0.00009178391,0.008033174,0.0002499379,0.0001456513,0.1833132,0.00009361524,0.00009724554,0.007113222],"study_design_scores_gemma":[0.0000419247,0.0003532265,0.9159645,0.00001630175,0.0000902297,0.04040038,0.0003800702,0.0007171712,0.04085611,0.00008823086,0.001083388,0.000008430918],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987564,0.0006195679,0.0002182391,0.000009075788,0.000002400344,0.000007810802,0.00002730135,0.000008287623,0.0003510061],"genre_scores_gemma":[0.999477,0.0001370084,0.0002291063,0.000004921858,0.000003082424,0.000004027057,0.00005880021,0.000001883623,0.00008427772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001538788,"threshold_uncertainty_score":0.00327462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008685815806064397,"score_gpt":0.2182401772945015,"score_spread":0.2095543614884371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}