{"id":"W2341972466","doi":"10.3389/fgene.2016.00059","title":"Gnaq and Gna11 in the Endothelin Signaling Pathway and Melanoma","year":2016,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"GNAQ; Computer science; Biology; Genetics; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007423485,0.0003507493,0.0001204106,0.0002900834,0.0001720975,0.0002782322,0.0001765038,0.0005556663,0.0009886911],"category_scores_gemma":[0.00003751225,0.00008136198,0.000184483,0.0001578262,0.0002929204,0.0004382058,0.0004142458,0.0005123729,0.0002823944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003177002,"about_ca_system_score_gemma":0.000144302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004893144,"about_ca_topic_score_gemma":0.0008103271,"domain_scores_codex":[0.999971,0.000004919096,0.000003052778,0.000004934931,0.000004950297,0.00001102917],"domain_scores_gemma":[0.9999828,0.00000269626,0.000005677652,6.456095e-7,0.000001848571,0.000006142243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006084168,0.00009522156,0.004002838,0.0008054349,0.00004361382,0.006754789,0.000372113,0.001367386,0.8385774,0.0504412,0.002698551,0.09423317],"study_design_scores_gemma":[0.00008431582,0.001084891,0.0612191,0.000360714,0.0001347046,0.03135738,0.001131631,0.004597533,0.2717996,0.04972149,0.5783922,0.0001164891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4813564,0.4568181,0.02150309,0.009151145,0.001138341,0.00006950615,0.0002188682,0.0002924717,0.02945206],"genre_scores_gemma":[0.6898022,0.256139,0.01073452,0.001912648,0.0006874055,0.00005398145,0.0002827929,0.00005186757,0.04033551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009886911,"threshold_uncertainty_score":0.003307521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007874161485182727,"score_gpt":0.2059437017270693,"score_spread":0.1980695402418866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}