{"id":"W2342006085","doi":"10.1093/neuonc/nov205.10","title":"ATNT-10DOES VALPROIC ACID IMPROVE SURVIVAL IN GLIOBLASTOMA? A META-ANALYSIS OF RANDOMIZED TRIALS IN NEWLY DIAGNOSED GLIOBLASTOMA","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Temozolomide; Medicine; Internal medicine; Hazard ratio; Oncology; Valproic Acid; Progression-free survival; Chemoradiotherapy; Post-hoc analysis; Confidence interval; Cancer; Epilepsy; Overall survival; Chemotherapy; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01506674,0.001925369,0.009028339,0.001632616,0.0004052412,0.002681826,0.001247939,0.001883373,0.002421637],"category_scores_gemma":[0.01680831,0.001098386,0.03159476,0.002229294,0.0006885421,0.001384782,0.001010366,0.002441016,0.0003048306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001296188,"about_ca_system_score_gemma":0.0009728497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003884735,"about_ca_topic_score_gemma":0.008642789,"domain_scores_codex":[0.988555,0.007863203,0.001584812,0.001132394,0.0005357221,0.0003288923],"domain_scores_gemma":[0.987192,0.00882922,0.002049166,0.0009791625,0.0005222145,0.0004282824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.04187651,0.00005328022,0.01120761,0.01957725,0.916182,0.000077842,0.00003917286,0.0006592675,0.0004781926,0.0001175685,0.0005033374,0.009227918],"study_design_scores_gemma":[0.008170596,0.001155839,0.01174089,0.001176739,0.9752308,0.00006572964,0.00004262413,0.0005854585,0.0002130189,0.0003590053,0.001236155,0.00002319435],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1424796,0.8513087,0.001708582,0.001059327,0.0009776291,0.0002831502,0.001073556,0.00009565332,0.001013717],"genre_scores_gemma":[0.9189902,0.07599864,0.0014188,0.001170711,0.0005472364,0.0002977545,0.0009532413,0.00005437415,0.0005689988],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01506674,"threshold_uncertainty_score":0.07968152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06600521054757182,"score_gpt":0.3632519645940265,"score_spread":0.2972467540464547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}