{"id":"W2342037372","doi":"10.1093/infdis/jiw004","title":"Low Prolactin and High 20-α-Hydroxysteroid Dehydrogenase Levels Contribute to Lower Progesterone Levels in HIV-Infected Pregnant Women Exposed to Protease Inhibitor–Based Combination Antiretroviral Therapy","year":2016,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Ovarian function and disorders","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Mount Sinai Hospital; University of Toronto; Women's College Hospital; University Health Network","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Ontario HIV Treatment Network; Canadian Foundation for AIDS Research","keywords":"Prolactin; Medicine; Human immunodeficiency virus (HIV); Antiretroviral therapy; Protease inhibitor (pharmacology); Pregnancy; Protease; Virology; Internal medicine; Endocrinology; Biology; Hormone; Viral load; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002414007,0.0001778067,0.0002244373,0.0002545947,0.0002158409,0.0004456398,0.0001112568,0.0001876152,0.0009285857],"category_scores_gemma":[0.0009266227,0.0002320678,0.0001796477,0.0002070831,0.0002393909,0.00009665771,0.0001505988,0.0004174771,0.0001117615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001900526,"about_ca_system_score_gemma":0.0001964852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001051668,"about_ca_topic_score_gemma":0.0009699031,"domain_scores_codex":[0.9998623,0.00004270169,0.00001043313,0.00002080805,0.00003932074,0.00002437965],"domain_scores_gemma":[0.9996768,0.0000764843,0.0001578991,0.00002001799,0.00002647354,0.00004228797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002464374,0.0001830838,0.8707746,0.0001280002,0.0001501456,0.00240419,0.0007230132,0.0001255123,0.09770309,0.0001072182,0.0002497004,0.02498712],"study_design_scores_gemma":[0.00002011527,0.0005112555,0.9891393,0.00002232413,0.00008743285,0.00310024,0.000357478,0.0003121103,0.00573974,0.00009111176,0.0006133981,0.000005538488],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978731,0.001323581,0.0001638994,0.00007796525,0.000007282719,0.000008980642,0.00005719655,0.000005657784,0.0004823564],"genre_scores_gemma":[0.9989334,0.0006096673,0.0001726199,0.00004201631,0.000008163414,0.000007827773,0.00004658247,0.000001654288,0.0001780847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001051668,"threshold_uncertainty_score":0.003106415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139876232353191,"score_gpt":0.2380402650782104,"score_spread":0.2266415027546785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}