{"id":"W2342037372","doi":"10.1093/infdis/jiw004","title":"Low Prolactin and High 20-α-Hydroxysteroid Dehydrogenase Levels Contribute to Lower Progesterone Levels in HIV-Infected Pregnant Women Exposed to Protease Inhibitor–Based Combination Antiretroviral Therapy","year":2016,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Ovarian function and disorders","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Mount Sinai Hospital; University of Toronto; Women's College Hospital; University Health Network","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Ontario HIV Treatment Network; Canadian Foundation for AIDS Research","keywords":"Prolactin; Medicine; Human immunodeficiency virus (HIV); Antiretroviral therapy; Protease inhibitor (pharmacology); Pregnancy; Protease; Virology; Internal medicine; Endocrinology; Biology; Hormone; Viral load; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006398705,0.0003050148,0.0005290969,0.0004916153,0.0001247979,0.00006678379,0.0001171542,0.00008952956,0.0001301528],"category_scores_gemma":[0.0007791994,0.0001734316,0.0001063591,0.0004743887,0.00008893215,0.0003270667,0.00004075779,0.0001980587,0.00002727855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003954749,"about_ca_system_score_gemma":0.0004018172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001080487,"about_ca_topic_score_gemma":0.00001295338,"domain_scores_codex":[0.9977767,0.0003819343,0.000655911,0.000251309,0.0004815511,0.0004525449],"domain_scores_gemma":[0.9980608,0.000219265,0.0003795917,0.0003025714,0.0004116081,0.0006261193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.03139102,0.007670046,0.428926,0.0002716667,0.0003994234,0.000266044,0.001738311,0.0002500176,0.5018778,0.00003411946,0.001021165,0.02615438],"study_design_scores_gemma":[0.07436705,0.02944519,0.7271355,0.003178749,0.0002657352,0.0003147032,0.0002964896,0.0001461831,0.163097,0.000394351,0.0005943121,0.0007647588],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914101,0.0001809063,0.002405251,0.003106331,0.0002595851,0.002463679,0.00008921051,0.00007030406,0.00001462205],"genre_scores_gemma":[0.9979327,0.0000201647,0.00002888433,0.001573179,0.0001308436,0.0001292377,0.000004823892,0.00004296863,0.0001371725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3387808,"threshold_uncertainty_score":0.7072337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139876232353191,"score_gpt":0.2380402650782104,"score_spread":0.2266415027546785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}