{"id":"W2342316284","doi":"10.1080/15476286.2015.1014759","title":"HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs","year":2015,"lang":"en","type":"article","venue":"RNA Biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"RNA interference; Biology; Small interfering RNA; RNA silencing; RNA-induced silencing complex; Gene silencing; RNA; microRNA; Trans-acting siRNA; HIV Long Terminal Repeat; Argonaute; Cell biology; Molecular biology; Gene expression; Gene; Genetics; Long terminal repeat","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003772588,0.0005201686,0.0004881765,0.0002824046,0.000179473,0.0005440082,0.0005463236,0.0004189073,0.001093119],"category_scores_gemma":[0.0002419856,0.0002945261,0.000485274,0.0001351134,0.0002642016,0.0002469732,0.0003091735,0.0006605079,0.0007354895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003156875,"about_ca_system_score_gemma":0.0001782589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002416884,"about_ca_topic_score_gemma":0.0003938039,"domain_scores_codex":[0.9995452,0.00007625458,0.00004534735,0.000113405,0.0001659335,0.0000538028],"domain_scores_gemma":[0.9998123,0.00005753699,0.00004162117,0.0000323683,0.00002608074,0.00003013672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001663578,0.000008696584,0.00006502229,0.00001601604,0.000004166685,0.00002313553,0.000004829671,0.00003426747,0.9991611,0.000109527,0.00001157461,0.0005449475],"study_design_scores_gemma":[0.000003305367,0.00004886513,0.0002931072,0.000001345533,0.00000580978,0.0001268018,0.000002825284,0.000785505,0.9979513,0.00001836577,0.0007606144,0.000002127507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9718703,0.003078004,0.02095626,0.0001150175,0.00005594665,0.00005703346,0.0002144745,0.0004465187,0.003206474],"genre_scores_gemma":[0.9813812,0.0007766713,0.01318596,0.00007352159,0.00001400723,0.00004108709,0.0004868234,0.00006638481,0.003974275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001093119,"threshold_uncertainty_score":0.003656864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0190745894896184,"score_gpt":0.271033076340988,"score_spread":0.2519584868513696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}