{"id":"W2342316284","doi":"10.1080/15476286.2015.1014759","title":"HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs","year":2015,"lang":"en","type":"article","venue":"RNA Biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"RNA interference; Biology; Small interfering RNA; RNA silencing; RNA-induced silencing complex; Gene silencing; RNA; microRNA; Trans-acting siRNA; HIV Long Terminal Repeat; Argonaute; Cell biology; Molecular biology; Gene expression; Gene; Genetics; Long terminal repeat","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002668042,0.0003061167,0.0003100089,0.00005805938,0.0001212116,0.00005563119,0.0004670797,0.0003407279,0.00006827245],"category_scores_gemma":[0.0001185982,0.0002514195,0.00007548984,0.00008607457,0.000174214,0.00001741162,0.000168374,0.0002016823,0.0001530295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000321345,"about_ca_system_score_gemma":0.0001863068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002337532,"about_ca_topic_score_gemma":0.0001529634,"domain_scores_codex":[0.9981958,0.0001806121,0.0002916246,0.0006562293,0.0001242678,0.0005514215],"domain_scores_gemma":[0.9988065,0.00002464197,0.0001694604,0.0005105832,0.0002010496,0.0002877373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000319735,0.00007789671,0.001291272,0.000008953539,0.00008523038,0.00001595336,0.0002427285,0.00005456046,0.9885173,0.00007311814,0.007646086,0.001667204],"study_design_scores_gemma":[0.001186293,0.002604174,0.0001782206,0.00003386031,0.00003418195,0.00008884435,0.00105584,0.0001526559,0.9478482,0.0001116069,0.04624079,0.0004653283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903595,0.001123689,0.0005965838,0.0003411555,0.0003371002,0.0001659317,0.0000876812,0.00003624381,0.006952119],"genre_scores_gemma":[0.9959228,0.0001286782,0.0004083058,0.0008199902,0.0005634265,0.00002026179,0.0008707511,0.00003842711,0.001227329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04066906,"threshold_uncertainty_score":0.9999938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0190745894896184,"score_gpt":0.271033076340988,"score_spread":0.2519584868513696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}