{"id":"W2342570238","doi":"10.1038/srep25220","title":"Cancer stem cells are underestimated by standard experimental methods in clear cell renal cell carcinoma","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; Princess Margaret Cancer Centre; University Health Network","funders":"Royal Australasian College of Physicians","keywords":"Clear cell renal cell carcinoma; Anoikis; Xenotransplantation; Cancer research; Cancer; Biology; Cell culture; Cell; Nod; Stem cell; Cell growth; Renal cell carcinoma; Cancer cell; Transplantation; Medicine; Pathology; Internal medicine; Cell biology; In vivo; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001224331,0.0002478405,0.0004806063,0.0002057229,0.0001373319,0.00009799028,0.0001055039,0.0001035249,0.001427568],"category_scores_gemma":[0.00001166567,0.0001735328,0.0001494211,0.0004651624,0.0003025788,0.0001284348,0.00009249194,0.0001439964,0.00002581949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000594881,"about_ca_system_score_gemma":0.00047272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003179816,"about_ca_topic_score_gemma":0.0000665877,"domain_scores_codex":[0.9969999,0.0001201981,0.0006640308,0.001029523,0.0006456277,0.0005407599],"domain_scores_gemma":[0.9982455,0.00004173293,0.0004017342,0.0008309538,0.0001454757,0.0003345821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001601083,0.000172985,0.004167861,0.00007471962,0.000009269413,0.0006261857,0.0002282121,0.000007940092,0.8987067,9.477045e-7,0.09116103,0.004683983],"study_design_scores_gemma":[0.001115949,0.00012871,0.0002892436,0.0001361904,0.00004673462,0.00004741251,0.0004127628,0.00001613124,0.8842798,0.00003343682,0.113291,0.0002025856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851665,0.005180142,0.001246898,0.0002733175,0.004646981,0.0005928495,0.00007881244,0.00006750853,0.002747006],"genre_scores_gemma":[0.9682459,0.00004575373,0.003942735,0.00006566411,0.00006319819,0.00005101596,0.0000140767,0.00004597214,0.02752565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02477865,"threshold_uncertainty_score":0.9994853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03294443164124623,"score_gpt":0.3403153150746616,"score_spread":0.3073708834334154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}