{"id":"W2342581347","doi":"10.3899/jrheum.151018","title":"Stabilization of Microcirculation in Patients with Early Systemic Sclerosis with Diffuse Skin Involvement following Rituximab Treatment: An Open-label Study","year":2016,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Vlaamse regering; Fonds Wetenschappelijk Onderzoek","keywords":"Medicine; Rituximab; Rheumatology; Microangiopathy; Internal medicine; Scleroderma (fungus); Fibrosis; Microcirculation; Thrombotic microangiopathy; Surgery; Gastroenterology; Disease; Dermatology; Pathology; Diabetes mellitus; Lymphoma","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004054355,0.000521838,0.003162619,0.0001886825,0.0003297246,0.0008296177,0.0006386686,0.001806289,0.002226923],"category_scores_gemma":[0.004427432,0.0002220254,0.0009742262,0.000455995,0.0006801161,0.0007182207,0.0001763285,0.0012507,0.0003702318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003244677,"about_ca_system_score_gemma":0.0004332503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001751255,"about_ca_topic_score_gemma":0.0002578788,"domain_scores_codex":[0.9990577,0.0005129642,0.000151705,0.0001043248,0.0001128061,0.00006052671],"domain_scores_gemma":[0.9921631,0.004468916,0.001592059,0.0003714673,0.0007720045,0.0006324264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7292817,0.01854035,0.04179882,0.01249992,0.007206924,0.003133998,0.000454085,0.0004389445,0.01180563,0.000274332,0.01216543,0.1623999],"study_design_scores_gemma":[0.2679409,0.5282106,0.1504501,0.00173937,0.01097313,0.003442847,0.0003456372,0.003320917,0.004324784,0.0005045385,0.0285482,0.000199],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9327393,0.05689781,0.0006280455,0.003307032,0.003132269,0.0009726189,0.0006690458,0.00004691011,0.001606985],"genre_scores_gemma":[0.968785,0.01229383,0.001106302,0.005356729,0.009552171,0.001219807,0.0005113691,0.00001603095,0.001158789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004054355,"threshold_uncertainty_score":0.0214417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03433909720476105,"score_gpt":0.2613286831856627,"score_spread":0.2269895859809016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}