{"id":"W2343151686","doi":"10.1371/journal.pone.0152073","title":"Characterization of CD200 Ectodomain Shedding","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; University Health Network; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Leukemia and Lymphoma Society of Canada; Leukemia and Lymphoma Society","keywords":"Ectodomain; HEK 293 cells; Extracellular; Molecular biology; Transfection; Cell culture; Flow cytometry; Cell biology; Western blot; Cytoplasm; Biology; Phosphorylation; Chemistry; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007675622,0.00005807758,0.0001508935,0.00005164571,0.0000328989,0.000002073276,0.00009389271,0.00004110242,0.00311523],"category_scores_gemma":[0.00009735311,0.00004226032,0.00002787237,0.00004380682,0.00004255316,0.00005547019,0.00003956567,0.00002036476,0.0004683182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001951134,"about_ca_system_score_gemma":0.00001244482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004067732,"about_ca_topic_score_gemma":0.000001702991,"domain_scores_codex":[0.9994797,0.00007765858,0.0001799063,0.0001096772,0.00002932225,0.0001237709],"domain_scores_gemma":[0.9995841,0.0001020022,0.00009427805,0.0001690202,0.00004190169,0.000008645054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003298286,0.0003317105,0.02552458,0.00003812567,0.0001580818,3.028186e-7,0.00003794417,7.180158e-9,0.9727749,0.0004802689,0.00008518059,0.0005358791],"study_design_scores_gemma":[0.0005317022,0.00005165541,0.03747887,0.0003063653,0.00004847991,8.432014e-7,0.000009528646,3.867955e-7,0.9609514,0.00006728771,0.0004914771,0.00006200307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986712,0.00009525589,0.0002086134,0.0001854177,0.00006997903,0.000169305,0.0001008727,0.000046049,0.0004533565],"genre_scores_gemma":[0.9981862,0.00001986544,0.00004434399,0.00002096276,0.00002365786,0.00001870297,0.00005853043,0.000007683085,0.001620073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01195429,"threshold_uncertainty_score":0.9977961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0348326508102317,"score_gpt":0.2247170670360894,"score_spread":0.1898844162258577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}