{"id":"W2343314930","doi":"10.1056/nejmoa1411627","title":"A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA","year":2015,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":356,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; Bavarian Nordic; Department for International Development; Public Health England; National Institute for Health and Care Research; Vaccine Research Center; Public Health Agency of Canada; Wellcome Trust; Philipps-Universität Marburg; GlaxoSmithKline; Public Health Agency; Università degli Studi di Napoli Federico II; NHS Blood and Transplant; World Health Organization","keywords":"Virology; Ebola vaccine; Ebola virus; Neutralizing antibody; Vaccination; Ebolavirus; Medicine; Titer; Antibody; Vaccinia; Vesicular stomatitis virus; Virus; Neutralization; Biology; Immunology; Recombinant DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007192875,0.0005464929,0.0005425313,0.0002731612,0.0001891311,0.0002863358,0.0003857535,0.0005875779,0.002101929],"category_scores_gemma":[0.0004502486,0.0002635083,0.0003198637,0.0001632806,0.0003875775,0.0003904052,0.0002444613,0.001073878,0.0003397389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002812867,"about_ca_system_score_gemma":0.0004063741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001002896,"about_ca_topic_score_gemma":0.00141829,"domain_scores_codex":[0.9997059,0.00007052776,0.00002116388,0.00009793622,0.000062859,0.0000416744],"domain_scores_gemma":[0.9997818,0.00005346216,0.00004166061,0.00003208554,0.00003685298,0.00005415032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.02494366,0.008372126,0.00497384,0.0008648052,0.0002558647,0.00007506156,0.0002541565,0.0007897033,0.9255,0.0001710518,0.0003542328,0.03344541],"study_design_scores_gemma":[0.008870545,0.4202144,0.03800086,0.0001392746,0.0006507343,0.0006665614,0.0002228295,0.002376459,0.5209449,0.000294486,0.007582124,0.00003685944],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970522,0.001115894,0.0007948445,0.00005552988,0.00008821622,0.000235789,0.0001284426,0.00004216963,0.0004870099],"genre_scores_gemma":[0.9953034,0.0005748944,0.002634361,0.00007291314,0.00003371628,0.0002011135,0.0002086103,0.000006801383,0.0009642431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002101929,"threshold_uncertainty_score":0.007031679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05762207696400846,"score_gpt":0.3368080528697932,"score_spread":0.2791859759057848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}