{"id":"W2343371293","doi":"10.1021/acs.chemmater.6b00627","title":"Transparent Porous Polysaccharide Cryogels Provide Biochemically Defined, Biomimetic Matrices for Tunable 3D Cell Culture","year":2016,"lang":"en","type":"article","venue":"Chemistry of Materials","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Self-healing hydrogels; 3D cell culture; Disaccharide; Polysaccharide; Chemical engineering; Polymer; Chemistry; Optical transparency; Materials science; Porosity; Nanotechnology; Polymer chemistry; Organic chemistry; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001650382,0.0003357753,0.0001345208,0.0001821756,0.000100886,0.0003498242,0.0002208328,0.0002716981,0.0008056167],"category_scores_gemma":[0.0001547842,0.0002283072,0.0001683661,0.00008428248,0.0003193601,0.0003316746,0.0003092551,0.0003756706,0.0002539239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001976897,"about_ca_system_score_gemma":0.0002159515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003191583,"about_ca_topic_score_gemma":0.001003387,"domain_scores_codex":[0.9999338,0.000008029219,0.000004675762,0.00001417594,0.0000213765,0.00001800152],"domain_scores_gemma":[0.9997925,0.00007480019,0.0000629362,0.00002495891,0.00001751503,0.00002731456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000005710156,0.000002748587,0.00003405552,0.00002011024,0.000001203801,0.00002589127,0.00001043908,0.0001227048,0.9989772,0.0001524998,0.00001580323,0.0006317451],"study_design_scores_gemma":[0.000002608451,0.00002333079,0.0003826607,0.00000385628,0.000003465819,0.00007840101,0.000007767119,0.0005210825,0.9975127,0.00005796656,0.001402319,0.00000384221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.914901,0.003181058,0.07646787,0.0001932856,0.00008364976,0.0000747387,0.0007701478,0.0003690818,0.003959241],"genre_scores_gemma":[0.9591874,0.001565608,0.03634495,0.00008260954,0.00001552971,0.00005662503,0.0002960306,0.00006741044,0.00238383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008056167,"threshold_uncertainty_score":0.002695084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01570953057224215,"score_gpt":0.2468881180454423,"score_spread":0.2311785874732001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}