{"id":"W2343430713","doi":"10.1038/srep25159","title":"FET proteins regulate lifespan and neuronal integrity","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; National Institutes of Health; Office of Research Infrastructure Programs, National Institutes of Health; Canadian Institutes of Health Research; AGE-WELL; ALS Society of Canada","keywords":"Amyotrophic lateral sclerosis; Caenorhabditis elegans; Phenotype; Biology; Neuroscience; Cell biology; Neurodegeneration; Disease; Bioinformatics; Medicine; Genetics; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006989649,0.000286407,0.0001103184,0.0001672429,0.0001957471,0.0002401812,0.000121354,0.000233596,0.0005652568],"category_scores_gemma":[0.00008725444,0.0000753598,0.0001083967,0.00006415452,0.000216295,0.0002745497,0.0001868251,0.0001988063,0.0001642644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003298633,"about_ca_system_score_gemma":0.0001223765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000550021,"about_ca_topic_score_gemma":0.0009773532,"domain_scores_codex":[0.9999574,0.000005062462,0.000003369051,0.00001198414,0.00001041945,0.00001178974],"domain_scores_gemma":[0.9999475,0.000005235398,0.00001852047,0.000003411101,0.00001206679,0.00001325768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009372696,0.00000662024,0.000640901,0.00002717403,0.000005518145,0.0001217836,0.00001463388,0.0001021942,0.9953445,0.0003636933,0.00009671397,0.00318248],"study_design_scores_gemma":[0.00002174654,0.0002413926,0.04031403,0.00002127041,0.00003286045,0.0008091727,0.00008507524,0.001490049,0.9465432,0.001086458,0.009337791,0.00001699787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983416,0.01012935,0.002860452,0.0001941776,0.00004252304,0.000009261161,0.0003053218,0.0001075082,0.002935485],"genre_scores_gemma":[0.9944765,0.002294061,0.001131354,0.00003357207,0.000008159096,0.000006013192,0.0001753651,0.00000840327,0.001866538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005652568,"threshold_uncertainty_score":0.002393365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01179532881397658,"score_gpt":0.2286359299202554,"score_spread":0.2168406011062788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}