{"id":"W2343515257","doi":"10.1371/journal.pcbi.1004894","title":"Nucleosome Presence at AML-1 Binding Sites Inversely Correlates with Ly49 Expression: Revelations from an Informatics Analysis of Nucleosomes and Immune Cell Transcription Factors","year":2016,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Ottawa","funders":"Ontario Research Foundation; Natural Sciences and Engineering Research Council of Canada; McGill University; Canadian Institutes of Health Research; University of Ottawa","keywords":"Nucleosome; Biology; Transcription factor; Gene; Gene expression; Genetics; Regulation of gene expression; Histone; SWI/SNF; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000491967,0.0001431823,0.000227731,0.0001318823,0.0001073489,0.00001280684,0.0001280747,0.0001375986,0.00004839697],"category_scores_gemma":[0.0000228438,0.00009957633,0.00006273029,0.0001403728,0.0001679625,0.00002137558,0.00007682497,0.00004160423,0.000003107297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001688083,"about_ca_system_score_gemma":0.00002926167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001287844,"about_ca_topic_score_gemma":0.00003653183,"domain_scores_codex":[0.999175,0.00005642415,0.0003329897,0.0002150646,0.00008754623,0.0001330484],"domain_scores_gemma":[0.99928,0.0001290582,0.000251783,0.0001699155,0.0001055284,0.0000636967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000556749,0.00005492966,0.1451367,0.00001100531,0.0002858619,1.776531e-7,0.0005663069,0.00501438,0.8486213,0.0001654629,0.00001038105,0.00007777214],"study_design_scores_gemma":[0.002876894,0.001534401,0.432862,0.0001246841,0.001083045,0.000006971376,0.001560731,0.1671489,0.3886999,0.002868308,0.0002791005,0.0009551177],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921958,0.0001085604,0.00685214,0.00005552399,0.00002939537,0.0001070155,0.0005968113,0.00001168471,0.00004299475],"genre_scores_gemma":[0.9887977,0.00007934476,0.00844409,0.00003024427,0.00001607932,0.000005124584,0.002576894,0.00001161487,0.00003886139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4599214,"threshold_uncertainty_score":0.4060605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092865256989809,"score_gpt":0.2135256640563128,"score_spread":0.2025970114864147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}