{"id":"W2343578718","doi":"10.1016/j.clim.2016.04.011","title":"Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation","year":2016,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Hematopoietic stem cell transplantation; Haematopoiesis; Stem cell; Transplantation; Immunology; Hematopoietic cell; Immunodeficiency; Medicine; Normalization (sociology); Cancer research; Biology; Immune system; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002450461,0.0003760495,0.0003376717,0.000205877,0.0001683069,0.0002094371,0.0001808659,0.0002744351,0.0005998199],"category_scores_gemma":[0.0002683659,0.00005763165,0.000216283,0.0001569931,0.0003752325,0.0001305195,0.0001945614,0.0005617116,0.0001662129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001656738,"about_ca_system_score_gemma":0.0001908035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000104357,"about_ca_topic_score_gemma":0.0001319696,"domain_scores_codex":[0.9999307,0.00001840386,0.000007635922,0.000007896923,0.00001437313,0.00002092158],"domain_scores_gemma":[0.9999012,0.00002014284,0.00001873916,0.00002196378,0.000007841612,0.00003009224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","study_design_scores_codex":[0.007736429,0.002621254,0.007246804,0.0003957913,0.0001151692,0.01943539,0.000202126,0.001765629,0.7418623,0.003256083,0.00245672,0.2129063],"study_design_scores_gemma":[0.002793671,0.02796509,0.1179006,0.0001632601,0.0005589644,0.09597253,0.0001866431,0.005746039,0.6955892,0.003934575,0.04911286,0.00007645003],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806161,0.005549976,0.007751054,0.0006551401,0.000168185,0.0001721842,0.0001485822,0.0002503417,0.00468838],"genre_scores_gemma":[0.9965124,0.001131111,0.0008580798,0.0001745584,0.00005416909,0.00005114374,0.0001985361,0.00001544706,0.001004467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005998199,"threshold_uncertainty_score":0.00200665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.046453143191949,"score_gpt":0.3241754056637064,"score_spread":0.2777222624717574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}