{"id":"W2343578718","doi":"10.1016/j.clim.2016.04.011","title":"Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation","year":2016,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Hematopoietic stem cell transplantation; Haematopoiesis; Stem cell; Transplantation; Immunology; Hematopoietic cell; Immunodeficiency; Medicine; Normalization (sociology); Cancer research; Biology; Immune system; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006633812,0.000202482,0.0004310263,0.00005249031,0.0001147078,0.000009638252,0.0001676419,0.0005317003,0.00004665464],"category_scores_gemma":[0.00008431669,0.0001422766,0.0003089171,0.00007156649,0.0005273517,0.00001114425,0.00008443529,0.0001216798,0.00002028735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001927531,"about_ca_system_score_gemma":0.00008756892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009736674,"about_ca_topic_score_gemma":0.000009897441,"domain_scores_codex":[0.997507,0.0004788081,0.001083201,0.0005578298,0.00009819068,0.0002749409],"domain_scores_gemma":[0.998834,0.0003207336,0.0003158365,0.0003723317,0.00009045022,0.00006669885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004284279,0.0006193168,0.162818,0.00002151751,0.0001647791,0.00001122917,0.00004423869,0.000003290432,0.8240898,0.0006419169,0.00002539734,0.01113216],"study_design_scores_gemma":[0.01175126,0.01320495,0.4028233,0.0001244057,0.0004577924,0.0001243679,0.0002535308,0.00001246574,0.5684128,0.0007386539,0.001422344,0.0006740874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990269,0.001848227,0.006716965,0.0001060904,0.0005516927,0.0001950662,0.00001895259,0.00002615159,0.0002678583],"genre_scores_gemma":[0.9969549,0.002272892,0.000169228,0.00005967664,0.0001114985,0.00002252293,0.00008933189,0.00001993768,0.0002999782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2556769,"threshold_uncertainty_score":0.5801872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.046453143191949,"score_gpt":0.3241754056637064,"score_spread":0.2777222624717574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}