{"id":"W2344059127","doi":"10.1038/ctg.2016.24","title":"Maintenance of Efficacy and Continuing Safety of Golimumab for Active Ulcerative Colitis: PURSUIT-SC Maintenance Study Extension Through 1 Year","year":2016,"lang":"en","type":"article","venue":"Clinical and Translational Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Western University","funders":"UCB Pharma; Janssen Scientific Affairs; Abbott Laboratories","keywords":"Golimumab; Medicine; Ulcerative colitis; Placebo; Internal medicine; Randomized controlled trial; Inflammatory bowel disease; Maintenance therapy; Population; Surgery; Disease; Infliximab; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003281213,0.0001184465,0.0002897404,0.00001641091,0.00003098054,0.000002753704,0.00007869655,0.00009134798,0.000009566787],"category_scores_gemma":[0.0002111388,0.00008642756,0.00009235876,0.00001495382,0.0005993505,0.00001015442,0.00004287468,0.00005464959,3.913721e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000024761,"about_ca_system_score_gemma":0.00002433955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001288234,"about_ca_topic_score_gemma":0.00004951293,"domain_scores_codex":[0.9987048,0.0001796911,0.0004973064,0.0003525217,0.00007887619,0.0001868026],"domain_scores_gemma":[0.999222,0.0001811745,0.0001822445,0.0001374977,0.0002146486,0.00006242701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.128745,0.00110913,0.8316814,0.00008097068,0.0005330149,0.00001769141,0.0005707326,0.00001836989,0.01388774,0.003905873,0.0002242366,0.01922588],"study_design_scores_gemma":[0.01178287,0.001926788,0.9846505,0.00007314564,0.00005563931,0.000006754889,0.0001076845,0.00001756292,0.0002854218,0.0007873629,0.0002425189,0.00006377261],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891545,0.00002729649,0.009438413,0.0003784396,0.00007406664,0.0005556562,0.0003289528,0.000003634054,0.00003909606],"genre_scores_gemma":[0.9985945,0.0001183628,0.0009964318,0.0001146054,0.00007306899,0.00002554961,0.00002304377,0.00001069114,0.00004377792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1529691,"threshold_uncertainty_score":0.3524413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01831503541777555,"score_gpt":0.3035362420280034,"score_spread":0.2852212066102278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}