{"id":"W2344059127","doi":"10.1038/ctg.2016.24","title":"Maintenance of Efficacy and Continuing Safety of Golimumab for Active Ulcerative Colitis: PURSUIT-SC Maintenance Study Extension Through 1 Year","year":2016,"lang":"en","type":"article","venue":"Clinical and Translational Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Western University","funders":"UCB Pharma; Janssen Scientific Affairs; Abbott Laboratories","keywords":"Golimumab; Medicine; Ulcerative colitis; Placebo; Internal medicine; Randomized controlled trial; Inflammatory bowel disease; Maintenance therapy; Population; Surgery; Disease; Infliximab; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002486662,0.0005739653,0.001139251,0.0003383392,0.0002931765,0.0004933423,0.0005455366,0.0007750944,0.00176156],"category_scores_gemma":[0.001208732,0.0002245204,0.0009700269,0.0002654532,0.0004927813,0.0006670922,0.0005037035,0.001420612,0.0003159332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004220031,"about_ca_system_score_gemma":0.000957184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005498724,"about_ca_topic_score_gemma":0.001085013,"domain_scores_codex":[0.9995208,0.0001940167,0.00004064842,0.00005989816,0.0000760805,0.0001085389],"domain_scores_gemma":[0.9986352,0.0001877546,0.000392139,0.0001513475,0.000121148,0.0005122975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8035659,0.04325927,0.02838442,0.0004468066,0.001044281,0.0001639555,0.000298073,0.0006167698,0.01802839,0.00008977513,0.0009132945,0.1031892],"study_design_scores_gemma":[0.2683624,0.6597633,0.06715074,0.0000389722,0.0005257768,0.0001704412,0.00004976403,0.000603743,0.002331751,0.00006771606,0.0009197093,0.00001563793],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983759,0.0004870774,0.00013896,0.00005398622,0.00001348589,0.0003980269,0.0001963225,0.00001785079,0.0003184988],"genre_scores_gemma":[0.9977219,0.0002989158,0.0003017042,0.0001204961,0.00006726912,0.0003794284,0.0005923857,0.000003235912,0.0005146954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002486662,"threshold_uncertainty_score":0.01315087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01831503541777555,"score_gpt":0.3035362420280034,"score_spread":0.2852212066102278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}