{"id":"W2344145345","doi":"10.1016/j.ymeth.2016.04.023","title":"Mutational analysis of FANCJ helicase","year":2016,"lang":"pl","type":"review","venue":"Methods","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Health","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society; Leukemia and Lymphoma Society of Canada","keywords":"Biology; Genetics; Helicase; Missense mutation; Fanconi anemia; Mutation; Genome instability; Gene; DNA repair; Cancer research; DNA; DNA damage; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008728547,0.001224577,0.0008375507,0.001747922,0.0002207817,0.0007983479,0.001270971,0.0008122037,0.001753625],"category_scores_gemma":[0.0009740105,0.0004176664,0.0003114289,0.001214646,0.0008915272,0.001096933,0.0006475223,0.001709078,0.001670332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009581791,"about_ca_system_score_gemma":0.0009420746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008909912,"about_ca_topic_score_gemma":0.0008503124,"domain_scores_codex":[0.999732,0.00002883299,0.00003063741,0.00007309605,0.0001071795,0.00002832916],"domain_scores_gemma":[0.9997079,0.0001166683,0.00004503758,0.00002411028,0.00007955556,0.00002661638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001146565,0.00007590924,0.000246349,0.0111881,0.00005549387,0.0002929129,0.0000408556,0.0003742639,0.0489721,0.007335031,0.03178247,0.8995219],"study_design_scores_gemma":[0.00002616819,0.00009783278,0.00101561,0.00131052,0.0001259621,0.002386113,0.00003021039,0.0003266225,0.04962736,0.003762092,0.9412518,0.00003975898],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008956195,0.9917369,0.003461688,0.000607413,0.0004118007,0.0000201213,0.0001071278,0.00008749049,0.002671738],"genre_scores_gemma":[0.006008284,0.9870493,0.002368789,0.0005422856,0.0002132787,0.00003146223,0.00027147,0.00001993954,0.003495336],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001753625,"threshold_uncertainty_score":0.006952047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04956062745938734,"score_gpt":0.4501775206021925,"score_spread":0.4006168931428052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}