{"id":"W2344240677","doi":"10.1111/tpj.13186","title":"<i>Rauvolfia serpentina N‐</i>methyltransferases involved in ajmaline and <i>N</i><sub>β</sub>‐methylajmaline biosynthesis belong to a gene family derived from γ‐tocopherol <i>C</i>‐methyltransferase","year":2016,"lang":"en","type":"article","venue":"The Plant Journal","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología; Canada Foundation for Innovation; Genome British Columbia; Genome Prairie; National Research Council Canada; Genome Canada; Genome Alberta; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs; McGill University","keywords":"Ajmaline; Methyltransferase; Biosynthesis; Gene; Gene family; Tocopherol; Genetics; Biology; Chemistry; Stereochemistry; Biochemistry; Methylation; Gene expression; Neuroscience; Vitamin E","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005962306,0.0004939312,0.0002264849,0.0001656435,0.0001743155,0.0003360291,0.0001729522,0.0002031045,0.0005740443],"category_scores_gemma":[0.0001183478,0.0001037907,0.0002849558,0.000141104,0.0001340137,0.0002005287,0.0002020897,0.0003723806,0.0004312638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002889638,"about_ca_system_score_gemma":0.0002423929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001024279,"about_ca_topic_score_gemma":0.0007488921,"domain_scores_codex":[0.9999378,0.000008501641,0.000005118657,0.00002243612,0.00001449883,0.00001162399],"domain_scores_gemma":[0.9999048,0.00001285266,0.00002908862,0.00001696096,0.0000160105,0.00002041013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003082649,0.000004523828,0.0002198764,0.0000142512,0.00000154428,0.0000294034,0.000009649278,0.00002494192,0.9984853,0.00003940547,0.000005650516,0.001134652],"study_design_scores_gemma":[0.000006271428,0.00009775563,0.01155729,0.000005807596,0.00001331343,0.0006251497,0.00003807053,0.0005078518,0.9826478,0.00006965975,0.004423766,0.000007202444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984049,0.001583422,0.01049632,0.0001375728,0.00002769307,0.00003962071,0.0007007206,0.0003037745,0.002661964],"genre_scores_gemma":[0.9843857,0.0008185969,0.008823975,0.00004676948,0.00000839992,0.00002424985,0.001905819,0.0000381479,0.003948275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001024279,"threshold_uncertainty_score":0.002096593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01314460194170607,"score_gpt":0.2047257084937559,"score_spread":0.1915811065520498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}