{"id":"W2344425664","doi":"10.1128/jvi.00224-16","title":"Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Svenska Läkaresällskapet; Linköpings Universitet; Svenska Sällskapet för Medicinsk Forskning; Svenska Forskningsrådet Formas; Styrelsen för Internationellt Utvecklingssamarbete; Vetenskapsrådet; George Cedric Metcalf Charitable Foundation","keywords":"Antibody opsonization; Herpes simplex virus; Biology; Complement system; Immune system; Virology; Antibody; Immunology; Complement receptor; Virus; Classical complement pathway; Alternative complement pathway; Opsonin","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001581852,0.0005297571,0.0002322139,0.0001681678,0.0001682477,0.0003391598,0.0001864649,0.0003352894,0.00258587],"category_scores_gemma":[0.0001976905,0.0000844102,0.0002435173,0.0001346258,0.0001992475,0.0001753873,0.0003490786,0.0004082772,0.0004500467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005214047,"about_ca_system_score_gemma":0.0003680775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001438591,"about_ca_topic_score_gemma":0.001283831,"domain_scores_codex":[0.999804,0.00003552925,0.00001156177,0.00002613191,0.00003817339,0.00008468183],"domain_scores_gemma":[0.999897,0.00003103029,0.00001492105,0.00001200397,0.00002746707,0.00001761647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000515657,0.0000748178,0.0003473403,0.0001370455,0.000007059284,0.0001486983,0.00003845839,0.00007779642,0.9961462,0.0001148799,0.0001322841,0.002259869],"study_design_scores_gemma":[0.00006012517,0.0008748519,0.008771406,0.00002395846,0.00002381004,0.0004595476,0.0000848433,0.0006762843,0.983525,0.00009846342,0.005394905,0.000006687573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895543,0.00495669,0.001207635,0.0001262319,0.00009818515,0.00008395794,0.0003036346,0.00004014957,0.00362932],"genre_scores_gemma":[0.9948552,0.001303851,0.0008910354,0.0001087954,0.00003266519,0.00005101897,0.0003160449,0.000008937229,0.002432516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00258587,"threshold_uncertainty_score":0.008650541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02821908791214372,"score_gpt":0.3285100543425932,"score_spread":0.3002909664304494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}