{"id":"W2345333765","doi":"10.3390/vaccines4020014","title":"Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences","year":2016,"lang":"en","type":"article","venue":"Vaccines","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pfizer (Canada)","funders":"","keywords":"CpG Oligodeoxynucleotide; TLR9; Adjuvant; TLR7; Nuclease; Endosome; Chemistry; CpG site; Antigen; Biology; Cell biology; Receptor; Molecular biology; Innate immune system; Biochemistry; Toll-like receptor; Immunology; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003750235,0.0005967594,0.0002606304,0.0001877102,0.00007176371,0.000202433,0.0001511882,0.0002594193,0.0009192734],"category_scores_gemma":[0.0004094324,0.0001201683,0.0001769991,0.0001966343,0.0002034438,0.0002396412,0.0001606209,0.0005008188,0.0001616213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001395615,"about_ca_system_score_gemma":0.0003090842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003662233,"about_ca_topic_score_gemma":0.0004752969,"domain_scores_codex":[0.9997678,0.00005795633,0.0000306561,0.00003197205,0.00004686353,0.00006475306],"domain_scores_gemma":[0.9995782,0.0001766887,0.00007768095,0.00001953546,0.00004863398,0.00009933289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001066254,0.0001595187,0.0001515469,0.000105883,0.000007493097,0.00002721226,0.00002163395,0.0002988689,0.9963624,0.00003167633,0.00001772244,0.001749875],"study_design_scores_gemma":[0.00004749067,0.0032803,0.001123394,0.00001189313,0.00002219824,0.00003468665,0.00001218533,0.0004367202,0.9945103,0.00001796167,0.0004969836,0.000005791017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980415,0.0008895191,0.0002903387,0.00002513287,0.00002806473,0.00002654238,0.0001254452,0.00001197701,0.000561432],"genre_scores_gemma":[0.9973415,0.0007349435,0.0009952552,0.00005180043,0.00002070355,0.00002524746,0.0001872956,0.0000108591,0.0006325087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009192734,"threshold_uncertainty_score":0.003075302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006588299633851692,"score_gpt":0.2186837181852074,"score_spread":0.2120954185513557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}