{"id":"W2345333765","doi":"10.3390/vaccines4020014","title":"Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences","year":2016,"lang":"en","type":"article","venue":"Vaccines","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pfizer (Canada)","funders":"","keywords":"CpG Oligodeoxynucleotide; TLR9; Adjuvant; TLR7; Nuclease; Endosome; Chemistry; CpG site; Antigen; Biology; Cell biology; Receptor; Molecular biology; Innate immune system; Biochemistry; Toll-like receptor; Immunology; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007742138,0.00009108391,0.0002280268,0.00008641396,0.00002746032,0.000001167971,0.0001068252,0.00008437662,0.0001819572],"category_scores_gemma":[0.0001938522,0.00004824219,0.00006801271,0.0000469236,0.00004251969,0.0000504002,0.00002703658,0.00003992353,0.0001120571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000877747,"about_ca_system_score_gemma":0.00001417525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002833697,"about_ca_topic_score_gemma":0.000004869569,"domain_scores_codex":[0.9994012,0.0001328387,0.0002219331,0.0001004681,0.00002302345,0.0001205695],"domain_scores_gemma":[0.9991722,0.0004811817,0.0001435112,0.0001455606,0.00005192655,0.000005677101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004374459,0.00006627365,0.00452168,0.00006880301,0.00006021955,7.133489e-7,0.00008317521,2.74416e-7,0.9803632,0.0008907509,0.0004991861,0.01300831],"study_design_scores_gemma":[0.000782999,0.0002640198,0.1806514,0.0001805153,0.00002035739,0.000002552621,0.00001175995,2.431781e-7,0.8172312,0.0002031227,0.0006009332,0.00005093282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984189,0.0005746715,0.00007684458,0.0002169236,0.000278454,0.0001245729,0.000003136087,0.00001787341,0.0002886337],"genre_scores_gemma":[0.9982514,0.0002336045,0.000006134581,0.00001465744,0.00001472717,0.000006504761,0.000003662729,0.000004819873,0.001464496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1761297,"threshold_uncertainty_score":0.1992304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006588299633851692,"score_gpt":0.2186837181852074,"score_spread":0.2120954185513557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}