{"id":"W2345341568","doi":"10.1038/mt.2016.91","title":"Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Medical Research Council; Wellcome Trust","keywords":"Mesenchymal stem cell; Transduction (biophysics); Viral vector; Biology; Genetic enhancement; Transgene; Gene delivery; Cell biology; Stromal cell; Ex vivo; Regenerative medicine; Virology; Cancer research; Stem cell; Gene; In vivo; Recombinant DNA; Biotechnology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004262198,0.0002703755,0.0003967599,0.0001976932,0.0001014314,0.00004417091,0.0001528265,0.0001233216,0.0006413006],"category_scores_gemma":[0.00002815606,0.0001818009,0.000128726,0.0002887,0.00009115196,0.00003838726,0.00005262209,0.0001447222,0.00006263323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001113711,"about_ca_system_score_gemma":0.0001434114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001329614,"about_ca_topic_score_gemma":0.000003100158,"domain_scores_codex":[0.9975649,0.0001718139,0.0002814355,0.000560974,0.0007314457,0.0006894768],"domain_scores_gemma":[0.9987745,0.00007114532,0.00001727345,0.0004960769,0.000125259,0.0005157845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009759145,0.0001729194,0.00006097654,0.00002443418,0.0001059442,0.0002421708,0.0002275923,0.0001136591,0.9865746,0.0001061989,0.00003313631,0.01136248],"study_design_scores_gemma":[0.003588092,0.0008947256,0.0006421502,0.0000685199,0.0000254119,0.00004354733,0.00002277276,0.001363305,0.9905301,0.0000114495,0.002578607,0.0002313261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9452947,0.001919409,0.05030576,0.0005824832,0.00009585611,0.001167826,0.00002654402,0.00004833072,0.0005590977],"genre_scores_gemma":[0.996887,0.0002467147,0.001762647,0.000419938,0.00008326014,0.00004160261,0.000003042602,0.0000698185,0.0004859483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05159234,"threshold_uncertainty_score":0.7413627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0469249560675318,"score_gpt":0.2944502081257624,"score_spread":0.2475252520582306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}