{"id":"W2345341568","doi":"10.1038/mt.2016.91","title":"Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Medical Research Council; Wellcome Trust","keywords":"Mesenchymal stem cell; Transduction (biophysics); Viral vector; Biology; Genetic enhancement; Transgene; Gene delivery; Cell biology; Stromal cell; Ex vivo; Regenerative medicine; Virology; Cancer research; Stem cell; Gene; In vivo; Recombinant DNA; Biotechnology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004073535,0.0004343855,0.0002743723,0.0004876251,0.0002113569,0.0003863248,0.0002373588,0.0003745747,0.0007690577],"category_scores_gemma":[0.0002744301,0.000149073,0.0003448751,0.0002436588,0.0003429781,0.000365364,0.000370982,0.000477549,0.000442912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002498016,"about_ca_system_score_gemma":0.000407549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005136188,"about_ca_topic_score_gemma":0.0005965292,"domain_scores_codex":[0.9997274,0.00004314659,0.00003441719,0.00005503602,0.00009576052,0.00004406939],"domain_scores_gemma":[0.9998535,0.00003701465,0.00003917667,0.0000222966,0.00002161469,0.00002636928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002618197,0.0000118402,0.00007717947,0.00002669432,0.000003257848,0.00005013401,0.00002318411,0.0000739789,0.994328,0.00036363,0.00003498957,0.004981024],"study_design_scores_gemma":[0.00001364815,0.0003251668,0.0004474742,0.000008631585,0.00001479408,0.0004339669,0.00001310608,0.0008792788,0.9903778,0.0001276691,0.007349744,0.000008704262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8134203,0.00451059,0.1768219,0.0002670298,0.0001593058,0.0003890851,0.0004789091,0.0008880552,0.003064882],"genre_scores_gemma":[0.8978457,0.002859107,0.09274705,0.00007653271,0.000056398,0.0002836666,0.001084743,0.0001327557,0.004914172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007690577,"threshold_uncertainty_score":0.002572715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0469249560675318,"score_gpt":0.2944502081257624,"score_spread":0.2475252520582306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}