{"id":"W2345506741","doi":"10.1016/j.cjca.2015.07.307","title":"SEPSIS-INDUCED MYOCARDIAL DEPRESSION IS ASSOCIATED WITH APOPTOSIS AND DIFFERENTIAL REGULATION OF S100A1, S100B, AND S100A6 AND THEIR RECEPTORS, RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS AND TOLL-LIKE RECEPTOR 4","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Medicine; Rage (emotion); Glycation; Receptor; Toll-like receptor; Sepsis; Depression (economics); TLR4; Internal medicine; Endocrinology; Neuroscience; Innate immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128779,0.0002786634,0.00031292,0.00022159,0.0001543641,0.0002197727,0.0001250613,0.0002737898,0.001170673],"category_scores_gemma":[0.0001742468,0.0001850183,0.0002707865,0.0001355711,0.0002578859,0.0001753863,0.0002555134,0.0008240491,0.0002215661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002120151,"about_ca_system_score_gemma":0.0001390948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002011301,"about_ca_topic_score_gemma":0.0002961617,"domain_scores_codex":[0.9998883,0.00001755205,0.000009734018,0.00001763363,0.00003012511,0.0000365983],"domain_scores_gemma":[0.9998519,0.00001032447,0.00006861717,0.0000100669,0.00002040961,0.00003856794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00237208,0.00008646344,0.002989656,0.00006307837,0.00002821881,0.000625128,0.00003618433,0.00005955049,0.9903843,0.0001513151,0.000109468,0.003094534],"study_design_scores_gemma":[0.0002961648,0.002105281,0.4835631,0.00005465101,0.0001520621,0.00478654,0.0003863568,0.002629789,0.5028124,0.0008163393,0.00235998,0.00003729009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957839,0.002390357,0.0008322429,0.0001353478,0.00003461797,0.00001268828,0.0001123721,0.00001812528,0.0006802494],"genre_scores_gemma":[0.9974207,0.0009918307,0.0003559363,0.00006121206,0.00001376076,0.00002009643,0.0001544364,0.000003869795,0.0009781544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001170673,"threshold_uncertainty_score":0.003916264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01323420381017618,"score_gpt":0.2162113516051171,"score_spread":0.2029771477949409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}