{"id":"W2345553021","doi":"10.7717/peerj.2461","title":"<i>Bcl-2</i> homologue <i>Debcl</i> enhances <i>α-synuclein</i> -induced phenotypes in <i>Drosophila</i>","year":2016,"lang":"en","type":"article","venue":"PeerJ","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Biology; Phenotype; Drosophila melanogaster; Transgene; Cell biology; Genetics; Neurodegeneration; Programmed cell death; Dopaminergic; Drosophila (subgenus); Population; Mitochondrion; Gene; Neuroscience; Apoptosis; Disease; Pathology; Dopamine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002187416,0.000357783,0.0005852849,0.0001606002,0.00009386019,0.00002579907,0.0001963286,0.0001658204,0.000247088],"category_scores_gemma":[0.000117203,0.0002352827,0.0001953924,0.0003288839,0.00007659979,0.0002003489,0.00008061521,0.0001544513,0.0008954269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001552855,"about_ca_system_score_gemma":0.0001409551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000131898,"about_ca_topic_score_gemma":0.00008522432,"domain_scores_codex":[0.9977642,0.00006744366,0.0004145521,0.0006765061,0.0004474684,0.0006297922],"domain_scores_gemma":[0.9987635,0.0001250378,0.0001208154,0.0005658634,0.00009180211,0.0003330035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007998178,0.002027757,0.03226836,0.0001190201,0.0002506886,0.001789243,0.0002270159,0.000001094849,0.8856105,0.00218789,0.006166894,0.06855172],"study_design_scores_gemma":[0.01926791,0.001545187,0.129921,0.0009422545,0.0005579672,0.0002977658,0.0001162153,0.00005278278,0.6349335,0.0104909,0.2005409,0.001333573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788592,0.001283285,0.0001523689,0.005244891,0.000497555,0.0005468684,0.00008064674,0.0002278275,0.0131073],"genre_scores_gemma":[0.9944685,0.0004491354,0.0006152877,0.001960126,0.0002514755,0.0001367326,0.00002551445,0.00006047391,0.002032817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.250677,"threshold_uncertainty_score":0.9998825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01932788470130115,"score_gpt":0.261762182706762,"score_spread":0.2424342980054608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}