{"id":"W2345587463","doi":"10.1038/ncomms11501","title":"14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Research Foundation of Korea; National Research Foundation","keywords":"RHEB; Gene knockdown; Cell biology; Gene isoform; Biology; Small GTPase; Signal transduction; Genetics; Gene; PI3K/AKT/mTOR pathway; mTORC1","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007876423,0.0003104379,0.0001431303,0.0002509058,0.0003334142,0.0002998609,0.0001868666,0.0002440966,0.001077651],"category_scores_gemma":[0.00008430675,0.0002107602,0.0003376401,0.0001189494,0.0002755808,0.0002108682,0.0003368075,0.0005452177,0.0006243569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006701713,"about_ca_system_score_gemma":0.000283618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001931347,"about_ca_topic_score_gemma":0.004953703,"domain_scores_codex":[0.9999087,0.000009705444,0.000005892614,0.00002338161,0.00002861073,0.00002371749],"domain_scores_gemma":[0.9999018,0.00001008211,0.00003391647,0.000009689247,0.00001691462,0.00002754199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000330825,0.000004225708,0.0004337212,0.00001036243,0.00000236706,0.00004152337,0.000009933138,0.00004084434,0.9986765,0.0001130978,0.00003906541,0.000595152],"study_design_scores_gemma":[0.00001396257,0.00004614831,0.03805823,0.000007846377,0.0000155805,0.0002460404,0.00004529329,0.002176137,0.9555765,0.000173902,0.003632449,0.000007728061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917367,0.001460195,0.003879247,0.0001295278,0.00003259753,0.00001565821,0.0004098833,0.0001373882,0.00219877],"genre_scores_gemma":[0.992749,0.0004884715,0.002503746,0.00006408238,0.000004371754,0.00001787119,0.0004933875,0.00005505712,0.003624038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001931347,"threshold_uncertainty_score":0.004862428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01499378261513959,"score_gpt":0.3087760953856499,"score_spread":0.2937823127705104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}