{"id":"W2345692188","doi":"10.5267/j.ccl.2016.2.002","title":"Design, synthesis and biological evaluation of 1,3,4-oxadiazoles/thiadiazoles bearing pyrazole scaffold as antimicrobial and antioxidant candidates","year":2016,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Pittsburgh","keywords":"Chemistry; Pyrazole; Antimicrobial; Thiadiazoles; Antioxidant; Scaffold; Combinatorial chemistry; Organic chemistry; Biomedical engineering","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005338225,0.0002670954,0.000352291,0.00002779396,0.00009696105,0.00003835605,0.0001759358,0.0001717529,0.0004593271],"category_scores_gemma":[0.0005289825,0.0001707595,0.0000785092,0.00005731062,0.0004454673,0.00009905158,0.0001392498,0.00011963,0.000006781636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007481388,"about_ca_system_score_gemma":0.00003786657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001860576,"about_ca_topic_score_gemma":5.066304e-7,"domain_scores_codex":[0.9985286,0.00006630809,0.0003073647,0.0005235185,0.0002521773,0.0003220556],"domain_scores_gemma":[0.9988481,0.0005251146,0.0002021843,0.0002245705,0.00006590638,0.0001340881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005876715,0.0000866535,0.0276273,0.0001378534,0.00004061506,0.000001790057,0.00001918908,0.000001400118,0.9119968,0.000004135363,0.0000698961,0.05995557],"study_design_scores_gemma":[0.000467797,0.000003060549,0.006502015,0.0004022289,0.00009046775,0.00002422319,0.00002105331,0.00008820041,0.9919804,0.00006289029,0.00007874297,0.0002788756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981743,0.0006775332,0.00008425986,0.0006702438,0.00004426572,0.00009583049,0.0000603277,0.00004838392,0.0001449001],"genre_scores_gemma":[0.9988666,0.0008183424,0.0001027341,0.00002309429,0.0001325238,0.0000330117,0.00000796263,0.0000127851,0.000002952563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07998362,"threshold_uncertainty_score":0.696337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04643718906586131,"score_gpt":0.264570121304628,"score_spread":0.2181329322387667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}