{"id":"W2346035244","doi":"10.1016/j.cmet.2016.04.012","title":"A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs","year":2016,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Human-Animal Interaction Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Dogs Trust; Royal Canin; Medical Research Council; National Institute for Health and Care Research; Wellcome Trust","keywords":"Labrador Retriever; Appetite; Allele; Obesity; Gene; Biology; Endocrinology; Body weight; Internal medicine; Coding region; Mutation; Genetics; Candidate gene; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002941004,0.0005189916,0.0004459436,0.0014716,0.0002177268,0.0002623869,0.0003627323,0.0005087202,0.00169718],"category_scores_gemma":[0.0005364617,0.0002050155,0.0003122224,0.0005583772,0.0006207015,0.0001415151,0.0002805371,0.000279489,0.0002687105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002117878,"about_ca_system_score_gemma":0.0001127687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001642326,"about_ca_topic_score_gemma":0.001656721,"domain_scores_codex":[0.99965,0.00006054434,0.00004017525,0.0001227254,0.00007569767,0.00005091649],"domain_scores_gemma":[0.9996021,0.00008248686,0.0002066289,0.00002774762,0.00002110295,0.00005996968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00331196,0.0004632818,0.2754563,0.0001429033,0.0003078003,0.01433751,0.0008438946,0.0003357157,0.6953666,0.00025351,0.0002871326,0.008893389],"study_design_scores_gemma":[0.00005284676,0.0004629318,0.9744141,0.00001318419,0.0001228014,0.0144572,0.000212562,0.0003734787,0.009137576,0.00004409566,0.0006927731,0.00001649016],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996197,0.00008757478,0.00008766118,0.00001046757,0.000001634737,0.00000224083,0.00007621039,0.00000587286,0.0001085458],"genre_scores_gemma":[0.9991014,0.0000894583,0.0001942187,0.00001777723,0.000008652467,0.000005858675,0.0003104787,0.000009367136,0.0002627506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00169718,"threshold_uncertainty_score":0.00567764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008164724773617703,"score_gpt":0.2463559493410653,"score_spread":0.2381912245674475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}