{"id":"W2346341352","doi":"10.1016/j.bbmt.2016.04.013","title":"Intravenous Busulfan-Based Myeloablative Conditioning Regimens Prior to Hematopoietic Cell Transplantation for Hematologic Malignancies","year":2016,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Office of Naval Research; U.S. Public Health Service; Onyx Pharmaceuticals; Health Resources and Services Administration; Otsuka Pharmaceutical; Miltenyi Biotec; Incyte; Telomere Diagnostics; Sunesis; Jazz Pharmaceuticals; Genentech; Seattle Genetics; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Therakos; Sigma-Tau Pharmaceuticals; Medical College of Wisconsin; University of Minnesota; Merck; Spectrum Pharmaceuticals; National Marrow Donor Program; St. Baldrick's Foundation; National Institute of Allergy and Infectious Diseases; Roswell Park Cancer Institute; Fred Hutchinson Cancer Research Center; Pharmacyclics; Health Research; National Cancer Institute; Gilead Sciences; Leukemia and Lymphoma Society; Genzyme; Alexion Pharmaceuticals; Be The Match Foundation; Otsuka America Pharmaceutical; Amgen; Celgene; HistoGenetics; WellPoint; Sanofi","keywords":"Medicine; Busulfan; Fludarabine; Cumulative incidence; Internal medicine; Cyclophosphamide; Transplantation; Hematopoietic stem cell transplantation; Incidence (geometry); Cohort; Myeloid; Hematopoietic cell; Oncology; Gastroenterology; Chemotherapy; Stem cell; Haematopoiesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002388528,0.0001349174,0.0002402561,0.000259136,0.0003436808,0.0002259845,0.000159672,0.00009902922,0.001311214],"category_scores_gemma":[0.00050667,0.00006621308,0.0001159269,0.0003305732,0.0001759394,0.0001996591,0.000267247,0.0003866758,0.0002336764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003725212,"about_ca_system_score_gemma":0.0004587371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001179792,"about_ca_topic_score_gemma":0.0029814,"domain_scores_codex":[0.9998211,0.00004259442,0.00001959634,0.00002910344,0.00004898644,0.00003862049],"domain_scores_gemma":[0.9997659,0.00002704935,0.0001006012,0.00002129292,0.0000178867,0.00006721205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009516756,0.003760007,0.6212094,0.0002589992,0.0002185598,0.0009495424,0.0004773472,0.001498359,0.06339792,0.0009713332,0.004132067,0.2936097],"study_design_scores_gemma":[0.0007165142,0.02060669,0.9460556,0.0001553469,0.0001291229,0.003631077,0.0001955953,0.001553811,0.01202569,0.0004273266,0.01447384,0.00002932376],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955128,0.001815539,0.0007828222,0.00006440053,0.00002152079,0.0001231117,0.0001289257,0.00001909777,0.001531834],"genre_scores_gemma":[0.9975793,0.0007541963,0.0007632641,0.0001165187,0.00003856536,0.00006803365,0.0002823684,0.000003992802,0.0003938476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001311214,"threshold_uncertainty_score":0.004386425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01382033834444136,"score_gpt":0.2515318138312221,"score_spread":0.2377114754867808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}