{"id":"W2346446766","doi":"10.1097/qad.0000000000001141","title":"Preexposure prophylaxis on-demand dramatically reduces HIV incidence in MSM","year":2016,"lang":"en","type":"letter","venue":"AIDS","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pill; Pre-exposure prophylaxis; Medicine; Human immunodeficiency virus (HIV); Men who have sex with men; Clinical trial; Incidence (geometry); Family medicine; Randomized controlled trial; Flexibility (engineering); Demography; Gynecology; Internal medicine; Pharmacology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004805207,0.000291237,0.0005639527,0.0005312165,0.00005534918,0.00005669436,0.0003813164,0.0006481458,0.002066428],"category_scores_gemma":[0.001444361,0.0001900565,0.0002770034,0.0002807457,0.0002359204,0.0001279047,0.0001146528,0.002088833,0.001896792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001589753,"about_ca_system_score_gemma":0.0002834868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003675731,"about_ca_topic_score_gemma":0.00000683895,"domain_scores_codex":[0.9971992,0.0002503803,0.0005423558,0.000514335,0.000867726,0.0006259457],"domain_scores_gemma":[0.9985487,0.000320758,0.0001030449,0.000683375,0.000176466,0.0001676004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006858057,0.00009364417,0.002197384,0.0005309493,0.00008821428,0.0008756646,0.0001092188,5.446436e-8,0.001036245,0.00006525752,0.9668001,0.02813469],"study_design_scores_gemma":[0.002324762,0.04596348,0.002374437,0.01439923,0.0001011841,0.0001376824,0.00004829599,0.0000395979,0.003635673,0.002342831,0.9279729,0.0006599289],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.1179488,0.0008108348,0.00050896,0.7785049,0.0002657149,0.002253877,0.0002217869,0.0001512384,0.09933385],"genre_scores_gemma":[0.2298371,0.0002425415,0.0015345,0.1344992,0.00667208,0.0005674119,0.0003402185,0.0001540567,0.6261529],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.6440058,"threshold_uncertainty_score":0.9988803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909624711722317,"score_gpt":0.3118950390572753,"score_spread":0.2927987919400521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}