{"id":"W2346770749","doi":"10.1016/s2213-8587(16)00112-1","title":"Survival and cardiovascular events in men treated with testosterone replacement therapy: an intention-to-treat observational cohort study","year":2016,"lang":"en","type":"article","venue":"The Lancet Diabetes & Endocrinology","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":156,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; Health Sciences Centre; Mount Sinai Hospital; Sunnybrook Health Science Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Government of Ontario; Physicians' Services Incorporated Foundation; Institute for Clinical Evaluative Sciences; Johns Hopkins University","keywords":"Medicine; Testosterone replacement; Database; Prostate cancer; Androgen deprivation therapy; Testosterone (patch); Comorbidity; Cohort; Population; Hormone replacement therapy (female-to-male); Cohort study; Internal medicine; Cancer; Androgen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005820339,0.0001783808,0.0006540972,0.00007414703,0.00007806278,0.000004080594,0.0001055727,0.00002235129,0.00001689474],"category_scores_gemma":[0.00007316867,0.00007838076,0.000041878,0.0001475622,0.0001405855,0.00005700369,0.000094145,0.00009577553,0.000007903905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005275913,"about_ca_system_score_gemma":0.0000166767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002079041,"about_ca_topic_score_gemma":0.0001174032,"domain_scores_codex":[0.9983094,0.0002588866,0.0001910218,0.00048551,0.0002443398,0.0005108248],"domain_scores_gemma":[0.9991276,0.0001044578,0.00003839231,0.0005565907,0.0001174635,0.00005546144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007788099,0.0003053884,0.9882267,0.000008037374,0.001167236,0.0000165318,0.000232862,0.000001831871,0.003385564,0.00006298709,0.00003800433,0.005776021],"study_design_scores_gemma":[0.005438222,0.002243701,0.9897183,0.00003212856,0.000156181,0.00001130555,0.0005769839,0.00000170544,0.001134188,0.00008618924,0.0004897889,0.0001112812],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928023,0.0007996531,0.000004599343,0.004475615,0.00004118476,0.001301564,0.00000807518,0.00004498853,0.0005220011],"genre_scores_gemma":[0.9984939,0.0003486905,0.00003448318,0.000136068,0.0001356442,0.0003575366,0.00001126377,0.00001669418,0.0004656957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005691605,"threshold_uncertainty_score":0.3196275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05578504886145688,"score_gpt":0.2914114295745438,"score_spread":0.2356263807130869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}