{"id":"W2347036634","doi":"10.3389/fmicb.2016.00608","title":"Bifidobacterium animalis ssp. lactis CNCM-I2494 Restores Gut Barrier Permeability in Chronically Low-Grade Inflamed Mice","year":2016,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Association Nationale de la Recherche et de la Technologie; Danone Nutricia Research; Crohn's and Colitis Foundation of Canada; Danone","keywords":"Bifidobacterium animalis; Intestinal permeability; Inflammation; Probiotic; Biology; Proinflammatory cytokine; Gut flora; Immunology; Immune system; Cytokine; Barrier function; Bifidobacterium; Microbiology; Cell biology; Bacteria; Fermentation; Lactobacillus; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002855397,0.0008153921,0.000858775,0.0008908113,0.0002444366,0.0004935309,0.0004802549,0.0007921401,0.001269429],"category_scores_gemma":[0.0002167417,0.000290318,0.000495141,0.0004653117,0.0003214479,0.0003288585,0.0003736429,0.001846214,0.0005091228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003907173,"about_ca_system_score_gemma":0.0003849924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001170784,"about_ca_topic_score_gemma":0.001222999,"domain_scores_codex":[0.999561,0.0000637609,0.00006042054,0.00008357475,0.0001184853,0.0001127554],"domain_scores_gemma":[0.9994234,0.00003525235,0.0002066379,0.0000557091,0.00004238302,0.0002366428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009315531,0.0002802543,0.0002057893,0.00005717638,0.00001267434,0.00007184497,0.0000146675,0.00005596684,0.9969686,0.00003168445,0.00005301468,0.00131684],"study_design_scores_gemma":[0.0002524717,0.008893602,0.01142455,0.00005316853,0.00008147264,0.0005011088,0.0001522768,0.0009878449,0.9739959,0.00009049784,0.003546597,0.00002050124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995023,0.001757263,0.001145707,0.0002190285,0.00006859986,0.00004115507,0.0007920869,0.0001718136,0.0007812917],"genre_scores_gemma":[0.9895455,0.001641737,0.002615033,0.0002788803,0.00003080123,0.0001324052,0.001796624,0.00008311894,0.003875849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001269429,"threshold_uncertainty_score":0.004246652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005849223833952629,"score_gpt":0.2350337174888535,"score_spread":0.2291844936549009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}