{"id":"W2347111419","doi":"10.1242/dev.125351","title":"Retinal development anomalies and cone photoreceptors degeneration upon Bmi1 deficiency","year":2016,"lang":"en","type":"article","venue":"Development","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Foundation Fighting Blindness","keywords":"Biology; Retinal degeneration; Degeneration (medical); Cone (formal languages); BMI1; Retinal; Retina; Cell biology; Neuroscience; Stem cell; Ophthalmology; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002831184,0.0002337925,0.0001418454,0.00007709456,0.0002269919,0.0000376871,0.000131658,0.0001139852,0.00009141261],"category_scores_gemma":[0.00005959999,0.0001732006,0.00002722194,0.00008052232,0.00007554457,0.00001026928,0.000140251,0.00003594431,0.00006336936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005530883,"about_ca_system_score_gemma":0.0003360541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002346496,"about_ca_topic_score_gemma":0.00005173938,"domain_scores_codex":[0.9985847,0.00003637499,0.0003504455,0.0004603083,0.0002314428,0.0003367673],"domain_scores_gemma":[0.999543,0.00001195682,0.00009184372,0.0001456797,0.00009007382,0.0001175217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002080835,0.000102781,0.1032593,0.00004547078,0.00006146931,0.000004899797,0.001002598,0.000001943439,0.772497,0.0003919518,0.003298592,0.1191259],"study_design_scores_gemma":[0.0006389259,0.00007640581,0.07441055,0.00003842517,0.00000486059,0.00001252978,0.0001102756,0.000001381354,0.6731093,0.00002530614,0.2511835,0.000388506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926099,0.0005628704,0.004194075,0.0001934997,0.0001822597,0.0002043925,0.000001951959,0.00002620748,0.002024913],"genre_scores_gemma":[0.9791483,0.000240223,0.01758526,0.00015671,0.00005342551,0.00007658633,0.0001032114,0.00002183798,0.002614409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.247885,"threshold_uncertainty_score":0.7062917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008243641009938994,"score_gpt":0.2105746569644911,"score_spread":0.2023310159545521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}