{"id":"W2347111419","doi":"10.1242/dev.125351","title":"Retinal development anomalies and cone photoreceptors degeneration upon Bmi1 deficiency","year":2016,"lang":"en","type":"article","venue":"Development","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Foundation Fighting Blindness","keywords":"Biology; Retinal degeneration; Degeneration (medical); Cone (formal languages); BMI1; Retinal; Retina; Cell biology; Neuroscience; Stem cell; Ophthalmology; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001034538,0.0004325767,0.0002163653,0.0005099645,0.0001408577,0.0002128234,0.0001602919,0.0002880841,0.001625804],"category_scores_gemma":[0.0001384699,0.000173821,0.0002232162,0.0001741309,0.0002685832,0.0001655309,0.0003179192,0.0005303525,0.0004064487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002044892,"about_ca_system_score_gemma":0.0002042512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007773931,"about_ca_topic_score_gemma":0.0009383587,"domain_scores_codex":[0.9998844,0.00001269618,0.00001524041,0.00002948512,0.00003858855,0.00001953874],"domain_scores_gemma":[0.9998394,0.0000162618,0.00005470407,0.00001690472,0.00001283454,0.00005984164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004900587,0.00000553449,0.0002779718,0.00001966904,0.000003793819,0.0001512792,0.00001023742,0.00002937097,0.9987918,0.00005641891,0.0000144042,0.000590416],"study_design_scores_gemma":[0.00001996714,0.0002629197,0.0420884,0.00001627202,0.00003895841,0.00389176,0.00005399918,0.0006011088,0.9501859,0.0001580755,0.002670898,0.00001179376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927235,0.001737,0.00266865,0.0000593337,0.00002442952,0.00002977275,0.0008910204,0.0001789854,0.001687292],"genre_scores_gemma":[0.9931236,0.001317476,0.001824794,0.00003624304,0.000007639515,0.00003364764,0.0007377508,0.00004197312,0.002876882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001625804,"threshold_uncertainty_score":0.005438864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008243641009938994,"score_gpt":0.2105746569644911,"score_spread":0.2023310159545521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}