{"id":"W2347362207","doi":"","title":"The influence of PTD-OD-HA fusion proteins on apoptosis of bcr/abl positive cell lines","year":2010,"lang":"en","type":"article","venue":"Tumori","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services","funders":"","keywords":"Apoptosis; K562 cells; Fusion protein; breakpoint cluster region; Molecular biology; Flow cytometry; Cell culture; Chemistry; ABL; Fusion gene; Blot; Biology; Cell biology; Cancer research; Signal transduction; Gene; Recombinant DNA; Tyrosine kinase; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001160462,0.0001076986,0.0001460319,0.00001987666,0.0001268516,0.00001079672,0.0002881613,0.00005365794,0.0001144761],"category_scores_gemma":[0.00009173754,0.00007508088,0.00006917825,0.0001004775,0.0001331179,0.00003218127,0.00005883776,0.0001907229,0.00003124382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008931827,"about_ca_system_score_gemma":0.00003944532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001296077,"about_ca_topic_score_gemma":0.00001353937,"domain_scores_codex":[0.9992446,0.00001070979,0.0002557891,0.0001641847,0.0001811757,0.0001435331],"domain_scores_gemma":[0.9989023,0.0002013881,0.0002218486,0.000488976,0.0001429458,0.00004249812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002462497,0.0001655604,0.0003245071,0.00004835234,0.000005587075,2.398035e-7,0.000116207,0.0000223735,0.9956148,0.001914295,0.00006971855,0.001693759],"study_design_scores_gemma":[0.0001169364,0.00003084186,0.00409269,0.00006014225,0.00001480002,0.000001051054,0.0001103118,0.00003355508,0.9934235,0.0003430494,0.001691381,0.00008176763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838211,0.00001947286,0.000005257258,0.0003037707,0.00002461573,0.0001379054,0.00004727552,0.0000214887,0.01561911],"genre_scores_gemma":[0.9986364,0.00003065338,0.0002882328,0.00001715014,0.0001034656,0.00007200056,0.000005206833,0.00001339276,0.0008335073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01481528,"threshold_uncertainty_score":0.3061709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005075150973313696,"score_gpt":0.2230833741344696,"score_spread":0.2180082231611559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}