{"id":"W2350852627","doi":"","title":"The anxiolytic effect and mechanism of indole derivate I_(20)","year":2002,"lang":"en","type":"article","venue":"","topic":"Organic Chemistry Cycloaddition Reactions","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Neuroactive steroid; Anxiolytic; Elevated plus maze; GABAA receptor; Benzodiazepine; Pharmacology; Chemistry; Receptor; Internal medicine; Open field; Sedation; Mechanism of action; Endocrinology; Medicine; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004688773,0.000218282,0.000121183,0.0001273044,0.0001002924,0.00008773469,0.00014528,0.0001293139,0.00191066],"category_scores_gemma":[0.00005001311,0.0000550098,0.0001465961,0.0000839926,0.0001439435,0.0001007984,0.00006814177,0.0002275587,0.0002668328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001575502,"about_ca_system_score_gemma":0.0001204085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007782788,"about_ca_topic_score_gemma":0.0007424251,"domain_scores_codex":[0.999979,0.000003479969,8.897142e-7,0.000002955806,0.000003162648,0.00001043695],"domain_scores_gemma":[0.9999774,0.000002827655,0.000008359358,0.000001924751,0.000003392141,0.000006158198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004917583,0.0000708207,0.000281925,0.00008881999,0.000006727872,0.0001737069,0.0000170373,0.0000952319,0.9931492,0.0001598822,0.00007505152,0.005389734],"study_design_scores_gemma":[0.00005444193,0.004597706,0.006882538,0.00001570004,0.0000347305,0.0006053276,0.00004031684,0.0003426977,0.9837819,0.00007720281,0.003557755,0.000009673318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874216,0.006022959,0.00132311,0.0001313472,0.00002201328,0.00003510165,0.0003004301,0.00004609425,0.00469723],"genre_scores_gemma":[0.9939756,0.002658567,0.001042278,0.00007472764,0.00001502093,0.00001476504,0.0001832736,0.000004120298,0.002031631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00191066,"threshold_uncertainty_score":0.006391764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005397843392810366,"score_gpt":0.1905157773175324,"score_spread":0.185117933924722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}