{"id":"W2351739364","doi":"10.1182/blood.v122.21.919.919","title":"Striking Predictive Power For Relapse and Decreased Survival Associated With Detectable Minimal Residual Disease by IGH VDJ Deep Sequencing Of Bone Marrow Pre- and Post-Allogeneic Transplant In Children With B-Lineage ALL: A Subanalysis Of The COG ASCT0431/PBMTC ONC051 Study","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of Manitoba","funders":"","keywords":"Minimal residual disease; Medicine; Internal medicine; Bone marrow; Oncology; Regimen; Cohort","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006250576,0.0002781405,0.0006963253,0.0001853014,0.0000835406,0.0000244787,0.0001460401,0.0001143606,0.00001149121],"category_scores_gemma":[0.0005401097,0.0001752838,0.00007039416,0.0004217934,0.0002559269,0.0001232348,0.00006740959,0.0002332543,4.544708e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001664942,"about_ca_system_score_gemma":0.0007710078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002230237,"about_ca_topic_score_gemma":0.001791704,"domain_scores_codex":[0.9975318,0.0002734731,0.0004988273,0.0004978682,0.0007549287,0.0004431554],"domain_scores_gemma":[0.9981997,0.0005752333,0.0002859747,0.0003518834,0.0003053084,0.0002819116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004887511,0.001395362,0.9496199,0.00009539907,0.003188423,0.00004300029,0.001703923,0.00004426731,0.03899047,0.000001224183,0.000006993559,0.00002354322],"study_design_scores_gemma":[0.02623831,0.003891726,0.951344,0.0003625884,0.005014061,0.00004935569,0.001310157,0.001665801,0.009926224,0.000003526144,1.980182e-7,0.0001940243],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957544,0.0004287176,0.00009718591,0.00006411604,0.000005310228,0.003039456,0.0005787942,0.00002007261,0.00001198329],"genre_scores_gemma":[0.999239,0.00001870608,0.0002949974,0.00002944829,0.00001370166,0.0001798475,0.0001325251,0.0000506996,0.00004103061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02906424,"threshold_uncertainty_score":0.7147865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006558864223106884,"score_gpt":0.2217966469818629,"score_spread":0.215237782758756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}