{"id":"W2367513127","doi":"10.1038/ejhg.2016.40","title":"The sub-nucleolar localization of PHF6 defines its role in rDNA transcription and early processing events","year":2016,"lang":"en","type":"article","venue":"European Journal of Human Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Ottawa Hospital Research Institute; Canadian Institutes of Health Research; Cancer Research Society; University of Ottawa","keywords":"Nucleolus; Ribosome biogenesis; Biology; Ribosomal RNA; RNA; Transcription (linguistics); Ribosome; Cell biology; Molecular biology; RNA polymerase I; Genetics; Gene; Nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008738392,0.0002370987,0.0001528087,0.0002258076,0.000202258,0.0002578857,0.0001456191,0.0003290344,0.001354108],"category_scores_gemma":[0.0001067737,0.0001090925,0.0002188954,0.0001315734,0.0002025257,0.0001768262,0.0001722676,0.0002749835,0.0005706768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002901127,"about_ca_system_score_gemma":0.0001303829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001026861,"about_ca_topic_score_gemma":0.001169508,"domain_scores_codex":[0.9998928,0.000007337824,0.000004811377,0.00004659472,0.00002764126,0.00002079479],"domain_scores_gemma":[0.9999405,0.000007504245,0.00001579979,0.000005588117,0.00001047744,0.00002006923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004917881,0.000004116163,0.0004760239,0.00002601508,0.000001801315,0.00003391081,0.00001061072,0.0000312927,0.9980508,0.00006520517,0.00003003192,0.001221073],"study_design_scores_gemma":[0.000009009049,0.00009171038,0.04673833,0.00001254187,0.00001137541,0.0009149722,0.00005426161,0.001090093,0.9431114,0.0002081626,0.007750474,0.00000774822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826757,0.004962271,0.008371841,0.0001057505,0.00003030734,0.00001940262,0.001405416,0.0001151079,0.002314232],"genre_scores_gemma":[0.9911762,0.001059999,0.00363311,0.00004328633,0.00001381323,0.00001336259,0.001284163,0.00002225433,0.002753753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001354108,"threshold_uncertainty_score":0.004529893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007793319921284633,"score_gpt":0.2074255352311107,"score_spread":0.1996322153098261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}