{"id":"W2367513127","doi":"10.1038/ejhg.2016.40","title":"The sub-nucleolar localization of PHF6 defines its role in rDNA transcription and early processing events","year":2016,"lang":"en","type":"article","venue":"European Journal of Human Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Ottawa Hospital Research Institute; Canadian Institutes of Health Research; Cancer Research Society; University of Ottawa","keywords":"Nucleolus; Ribosome biogenesis; Biology; Ribosomal RNA; RNA; Transcription (linguistics); Ribosome; Cell biology; Molecular biology; RNA polymerase I; Genetics; Gene; Nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004075298,0.00008065774,0.00009106019,0.00003838424,0.00007326324,0.00001957859,0.0001572043,0.00002664912,9.681251e-7],"category_scores_gemma":[0.00002277734,0.00005306991,0.00004048928,0.00003610978,0.00005233236,0.000005666782,0.00003505334,0.00004754845,6.251097e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007529203,"about_ca_system_score_gemma":0.00002237371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.037153e-7,"about_ca_topic_score_gemma":0.000009693795,"domain_scores_codex":[0.9992023,0.0001261386,0.0003781383,0.00008951352,0.00009867597,0.0001052201],"domain_scores_gemma":[0.9994552,0.000004848876,0.000273486,0.00009607855,0.0001330689,0.0000373586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002935603,0.00002442789,0.01344043,0.0000160287,0.00001267906,0.000002281299,0.0001872401,0.000142753,0.9690278,0.00002039471,0.00001472599,0.01708193],"study_design_scores_gemma":[0.003241506,0.002130527,0.4185025,0.0004158995,0.00007671975,0.00009184459,0.0002984002,0.0008325474,0.5675045,0.000916469,0.005616636,0.0003724387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992923,0.004593471,0.002240785,0.00004323551,0.00004344637,0.00004992446,0.000002476223,0.000001108303,0.0001025929],"genre_scores_gemma":[0.9978773,0.001783385,0.0001776667,0.00001380303,0.00008037888,2.458645e-7,0.00000144268,0.00002103689,0.00004473914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4050621,"threshold_uncertainty_score":0.2164128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007793319921284633,"score_gpt":0.2074255352311107,"score_spread":0.1996322153098261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}