{"id":"W2374560515","doi":"","title":"Histone Acetylation and Cancer","year":2003,"lang":"en","type":"article","venue":"PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Histone methyltransferase; Histone H2A; Histone methylation; Histone; Histone code; Histone Acetyltransferases; SAP30; Acetylation; Histone H1; Biology; Chromatin; HDAC4; Histone-modifying enzymes; Chromatin remodeling; Genetics; Chemistry; Cell biology; Gene; DNA methylation; Nucleosome; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001233962,0.0001404129,0.0001127435,0.00002386326,0.00007093277,0.00002444057,0.00006393923,0.0001540422,0.000006694089],"category_scores_gemma":[0.00003646857,0.0001409245,0.0000239544,0.0001175885,0.0003212529,0.000005151569,0.0000630369,0.0001184941,0.000001136457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002723763,"about_ca_system_score_gemma":0.00006337161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007894068,"about_ca_topic_score_gemma":0.000003839917,"domain_scores_codex":[0.9991355,0.00003270114,0.0001334314,0.0003684611,0.0001121316,0.0002177799],"domain_scores_gemma":[0.9996371,0.000006777381,0.00004547818,0.0001791914,0.00004789971,0.00008357765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004860849,0.00009202829,0.02016922,0.0001152573,0.00001605953,0.000004809026,0.00005335434,0.000001338739,0.9581868,0.00013767,0.0002270084,0.02094785],"study_design_scores_gemma":[0.0004391084,0.00004886793,0.0009895704,0.00003092314,0.000005828439,0.00001320397,0.00003622379,0.00003162103,0.991665,0.00006987308,0.006483134,0.0001866266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840701,0.01513937,0.00001661864,0.0001215295,0.00004716571,0.0001116102,0.00001340555,0.000008338753,0.0004719082],"genre_scores_gemma":[0.9977226,0.001117957,0.0004368426,0.00003324003,0.0001118263,0.00005774645,0.00003752933,0.00001478188,0.00046753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03347822,"threshold_uncertainty_score":0.5746734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009860844630927137,"score_gpt":0.3097265162885565,"score_spread":0.2998656716576294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}