{"id":"W2374562229","doi":"10.1016/j.ebiom.2016.05.007","title":"Will LEDGIN molecules be able to play a role in a cure for HIV infection?","year":2016,"lang":"en","type":"letter","venue":"EBioMedicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Virology; Integrase; Raltegravir; Integrase inhibitor; Viral replication; Reverse transcriptase; Biology; Medicine; Immunology; Viral load; Human immunodeficiency virus (HIV); Virus; Antiretroviral therapy; Polymerase chain reaction; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002074496,0.0003119942,0.0005306054,0.0006139767,0.00009553823,0.000009452095,0.0002028744,0.0007245355,0.00146],"category_scores_gemma":[0.0001033362,0.0002057932,0.0001083925,0.0001962869,0.0001724993,0.00004434901,0.00007791623,0.0006866603,0.00209455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001878314,"about_ca_system_score_gemma":0.0001400545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003820916,"about_ca_topic_score_gemma":0.0001653728,"domain_scores_codex":[0.9982151,0.0001161789,0.0002897901,0.0004986771,0.00007562913,0.0008045941],"domain_scores_gemma":[0.9991876,0.0002484962,0.00007079815,0.0003647918,0.00007607943,0.00005219958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001375573,0.00007063753,0.0004553979,0.00007024617,0.0002597205,0.0001470136,0.0002044712,2.031511e-7,0.01233791,0.00002426969,0.9833761,0.002916487],"study_design_scores_gemma":[0.003933091,0.0008494537,0.0002501092,0.0003002577,0.00004586964,0.00005030759,0.00001492698,3.776713e-7,0.001586904,0.0002388219,0.9925225,0.0002073314],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002280639,0.003009123,0.0006248343,0.9866883,0.0007588708,0.001627578,0.001785324,0.0000820303,0.003143283],"genre_scores_gemma":[0.01541315,0.0006796466,0.0004272011,0.560396,0.005990529,0.003972721,0.02309312,0.0002326019,0.3897951],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.4262924,"threshold_uncertainty_score":0.9994528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01047764118567283,"score_gpt":0.2776514090605913,"score_spread":0.2671737678749184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}