{"id":"W2375054951","doi":"10.1039/9781782620105-00062","title":"Well-Defined Cationic Polymers for Nucleic Acid Delivery","year":2014,"lang":"en","type":"book-chapter","venue":"","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Cationic polymerization; Gene delivery; Nucleic acid; Living cationic polymerization; Genetic enhancement; Chemistry; Polymer; DNA; Polymerization; Chain transfer; Cationic liposome; Biophysics; Combinatorial chemistry; Gene; Radical polymerization; Biochemistry; Biology; Polymer chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002855389,0.001020942,0.0004231504,0.001006293,0.0003154679,0.0009505058,0.000631306,0.0007414345,0.012096],"category_scores_gemma":[0.0002255419,0.000360951,0.0002820752,0.001025356,0.0003710162,0.001853448,0.0007968408,0.001845088,0.01068808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005859883,"about_ca_system_score_gemma":0.0003532148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001387695,"about_ca_topic_score_gemma":0.000280851,"domain_scores_codex":[0.9997659,0.00001773471,0.00001233484,0.00005215465,0.0001337458,0.00001814814],"domain_scores_gemma":[0.9999436,0.00001935464,0.000007790809,0.000004417055,0.00001724776,0.000007550665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008515396,0.000168165,0.00006346822,0.003352064,0.00002960943,0.000481513,0.0003799257,0.001822109,0.2563594,0.1425226,0.05183328,0.5429026],"study_design_scores_gemma":[0.00001220008,0.00007797645,0.00006718701,0.0002024193,0.000008157918,0.0006017548,0.00001921728,0.0005101154,0.05007846,0.007866897,0.940529,0.00002667374],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01087982,0.6124353,0.1054375,0.001565488,0.004047041,0.0003731374,0.0005157598,0.001112984,0.2636329],"genre_scores_gemma":[0.04541244,0.4649473,0.07789529,0.001794553,0.0009502309,0.0005411806,0.0007733992,0.0004600506,0.4072257],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.012096,"threshold_uncertainty_score":0.04046512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137329387341087,"score_gpt":0.2214149033741887,"score_spread":0.2100416095007778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}