{"id":"W2376377197","doi":"10.1007/s00726-016-2246-8","title":"Polyamine–DNA interactions and development of gene delivery vehicles","year":2016,"lang":"en","type":"review","venue":"Amino Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"Polyamine; Nucleic acid; DNA condensation; DNA; Biophysics; Chemistry; Gene delivery; Macromolecule; Biochemistry; Spermine; Combinatorial chemistry; Gene; Biology; Genetic enhancement; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007567821,0.0002692704,0.000511142,0.0001012821,0.00005183522,0.00001357504,0.0002204314,0.0002165108,0.00003189842],"category_scores_gemma":[0.00001969646,0.000200754,0.0001568847,0.00004570058,0.00008450533,0.000004861496,0.0001754871,0.00008405084,0.00005723872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000206276,"about_ca_system_score_gemma":0.0002267575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005024157,"about_ca_topic_score_gemma":0.00001556951,"domain_scores_codex":[0.9988863,0.00004500325,0.0004371469,0.0003593761,0.00008657105,0.0001856002],"domain_scores_gemma":[0.9993081,0.00002381795,0.0002047365,0.0003201922,0.00007790942,0.00006526166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008317853,0.00002534674,0.00002192741,0.0006904796,0.0002269486,0.000002246177,0.00002833835,1.376726e-8,0.03347415,0.000003333829,0.0005275586,0.9649913],"study_design_scores_gemma":[0.0001036422,0.00008658702,0.00005905009,0.001649902,0.00008785348,0.00004485706,0.00002111076,1.320206e-7,0.04007437,0.000001624346,0.9576238,0.000247022],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02289302,0.9761237,0.0002265828,0.000004914928,0.0001856791,0.0001472587,0.00007362627,0.000006776664,0.0003384199],"genre_scores_gemma":[0.003046615,0.9941314,0.0008578332,0.00002713275,0.0001889512,0.0000384076,0.0002473711,0.00002862941,0.001433595],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9647443,"threshold_uncertainty_score":0.818651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03318952175716611,"score_gpt":0.3011122273038321,"score_spread":0.267922705546666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}