{"id":"W2376717750","doi":"10.1358/dot.2013.49.12.2067249","title":"Simeprevir for the treatment of genotype 1 chronic hepatitis Cvirus","year":2013,"lang":"en","type":"article","venue":"Drugs of today","topic":"Hepatitis C virus research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Simeprevir; Ribavirin; Medicine; Pegylated interferon; Virology; Hepatitis C virus; Genotype; Protease inhibitor (pharmacology); Interferon; Internal medicine; Pharmacology; Virus; Viral load; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001416824,0.0001109303,0.0003228112,0.00006410621,0.00004667381,0.000007171642,0.0001393521,0.00005951884,0.001487568],"category_scores_gemma":[0.0001080574,0.00006737033,0.0001727842,0.0001146764,0.0001288266,0.00005023852,0.00002472178,0.00005358967,0.000183717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001711318,"about_ca_system_score_gemma":0.0001813009,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007474995,"about_ca_topic_score_gemma":0.0002837107,"domain_scores_codex":[0.9990039,0.00003505799,0.0002856505,0.0001563697,0.0002739843,0.0002450179],"domain_scores_gemma":[0.9987078,0.0004076562,0.00008794542,0.000486388,0.0002276494,0.00008250099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001056505,0.0004250241,0.01932523,0.0002759616,0.0003741362,0.000002500198,0.001059681,0.00001699152,0.02125551,0.0003746626,0.008030368,0.9487543],"study_design_scores_gemma":[0.003957648,0.00509089,0.06689584,0.0001575573,0.0002485477,0.000002314066,0.00008719882,0.004378816,0.2103232,0.0002586593,0.7084094,0.000189951],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780219,0.008670502,0.0002055959,0.002633366,0.000153364,0.003200869,0.0001101955,0.00002833537,0.006975858],"genre_scores_gemma":[0.9887009,0.006023518,0.000606888,0.00007436613,0.0001719452,0.000353388,0.00002004083,0.00002485901,0.004024133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9485644,"threshold_uncertainty_score":0.9994252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02708515269192192,"score_gpt":0.3213115087311132,"score_spread":0.2942263560391913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}